E78 — Disorders of lipoprotein metabolism and other lipidemias
Is E78 billable?
No — E78 is a non-billable header code. E78 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 18 billable codes beneath E78.
Billable codes under this header
- E78.1Pure hyperglyceridemia
- E78.2Mixed hyperlipidemia
- E78.3Hyperchylomicronemia
- E78.5Hyperlipidemia, unspecified
- E78.6Lipoprotein deficiency
- E78.9Disorder of lipoprotein metabolism, unspecified
- E78.00Pure hypercholesterolemia, unspecified
- E78.41Elevated Lipoprotein(a)
- E78.49Other hyperlipidemia
- E78.70Disorder of bile acid and cholesterol metabolism, unspecified
- E78.71Barth syndrome
- E78.72Smith-Lemli-Opitz syndrome
- E78.79Other disorders of bile acid and cholesterol metabolism
- E78.81Lipoid dermatoarthritis
- E78.89Other lipoprotein metabolism disorders
- E78.010Homozygous familial hypercholesterolemia [HoFH]
- E78.011Heterozygous familial hypercholesterolemia [HeFH]
- E78.019Familial hypercholesterolemia, unspecified
E78 at a glance
| Code | E78 |
|---|---|
| Description | Disorders of lipoprotein metabolism and other lipidemias |
| Billable | No — header code |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Excludes1 — never code together
The conditions below can never be reported together with E78 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- sphingolipidosis (E75.0-E75.3)
Excludes1 — never code together — inherited from Chapter 4
The conditions below can never be reported together with E78 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Excludes1 — never code together — inherited from E70-E88
The conditions below can never be reported together with E78 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes2 — not included here — inherited from E70-E88
The conditions below are not part of E78, but a patient may have both at the same time. When documentation supports it, E78 and the excluded code may both be reported.
- Ehlers-Danlos syndromes (Q79.6-)
What codes fall under E78? (10)
- E78.0Pure hypercholesterolemianot billable
- E78.1Pure hyperglyceridemia
- E78.2Mixed hyperlipidemia
- E78.3Hyperchylomicronemia
- E78.4Other hyperlipidemianot billable
- E78.5Hyperlipidemia, unspecified
- E78.6Lipoprotein deficiency
- E78.7Disorders of bile acid and cholesterol metabolismnot billable
- E78.8Other disorders of lipoprotein metabolismnot billable
- E78.9Disorder of lipoprotein metabolism, unspecified
How long has E78 existed?
E78 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
Which codes are confused with E78?
ICD-10-CM declares these codes mutually exclusive with E78 — exactly one of each pair can be correct for a given encounter.