ICDcodes.org
FY2027

E75.3 vs E78

E75.3 and E78 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.

The official note, declared on E78
sphingolipidosis (E75.0-E75.3)
E75.3

Sphingolipidosis, unspecified

BillableUnspecified
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E70-E88
Indexed under
  • Sphingolipidosis
  • Sphingomyelinosis
  • Degeneration, degenerative › brain › in › sphingolipidosis
E78

Disorders of lipoprotein metabolism and other lipidemias

Not billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E70-E88

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027