E72 — Other disorders of amino-acid metabolism
Is E72 billable?
No — E72 is a non-billable header code. E72 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 31 billable codes beneath E72.
Billable codes under this header
- E72.3Disorders of lysine and hydroxylysine metabolism
- E72.4Disorders of ornithine metabolism
- E72.9Disorder of amino-acid metabolism, unspecified
- E72.00Disorders of amino-acid transport, unspecified
- E72.01Cystinuria
- E72.02Hartnup's disease
- E72.03Lowe's syndrome
- E72.04Cystinosis
- E72.09Other disorders of amino-acid transport
- E72.10Disorders of sulfur-bearing amino-acid metabolism, unspecified
- E72.11Homocystinuria
- E72.12Methylenetetrahydrofolate reductase deficiency
- E72.19Other disorders of sulfur-bearing amino-acid metabolism
- E72.20Disorder of urea cycle metabolism, unspecified
- E72.21Argininemia
- E72.22Arginosuccinic aciduria
- E72.23Citrullinemia
- E72.29Other disorders of urea cycle metabolism
- E72.50Disorder of glycine metabolism, unspecified
- E72.51Non-ketotic hyperglycinemia
- E72.52Trimethylaminuria
- E72.59Other disorders of glycine metabolism
- E72.81Disorders of gamma aminobutyric acid metabolism
- E72.89Other specified disorders of amino-acid metabolism
- E72.530Primary hyperoxaluria, type 1
- E72.538Other specified primary hyperoxaluria
- E72.539Primary hyperoxaluria, unspecified
- E72.540Dietary hyperoxaluria
- E72.541Enteric hyperoxaluria
- E72.548Other secondary hyperoxaluria
- E72.549Secondary hyperoxaluria, unspecified
E72 at a glance
| Code | E72 |
|---|---|
| Description | Other disorders of amino-acid metabolism |
| Billable | No — header code |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Excludes1 — never code together
The conditions below can never be reported together with E72 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from Chapter 4
The conditions below can never be reported together with E72 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Excludes1 — never code together — inherited from E70-E88
The conditions below can never be reported together with E72 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes2 — not included here — inherited from E70-E88
The conditions below are not part of E72, but a patient may have both at the same time. When documentation supports it, E72 and the excluded code may both be reported.
- Ehlers-Danlos syndromes (Q79.6-)
What codes fall under E72? (8)
- E72.0Disorders of amino-acid transportnot billable
- E72.1Disorders of sulfur-bearing amino-acid metabolismnot billable
- E72.2Disorders of urea cycle metabolismnot billable
- E72.3Disorders of lysine and hydroxylysine metabolism
- E72.4Disorders of ornithine metabolism
- E72.5Disorders of glycine metabolismnot billable
- E72.8Other specified disorders of amino-acid metabolismnot billable
- E72.9Disorder of amino-acid metabolism, unspecified
How long has E72 existed?
E72 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
Which codes are confused with E72?
ICD-10-CM declares these codes mutually exclusive with E72 — exactly one of each pair can be correct for a given encounter.