E72.81 — Disorders of gamma aminobutyric acid metabolism
Is E72.81 billable?
Yes — E72.81 is billable for FY2027. E72.81 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E72.81 may be submitted for encounters from October 1, 2026 through September 30, 2027.
E72.81 at a glance
| Code | E72.81 |
|---|---|
| Description | Disorders of gamma aminobutyric acid metabolism |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does E72.81 group to?
E72.81 sits in MDC 10 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 642Inborn and Other Disorders of Metabolismmedical
As a secondary diagnosis, E72.81 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is E72.81 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to E72.81. They show the wording a clinician may have documented, which often differs from the Tabular description.
- SSADHD (succinic semialdehyde dehydrogenase deficiency)
- Aciduria › 4-hydroxybutyric
- Aciduria › gamma-hydroxybutyric
- Defect, defective › GABAmetabolic
- Deficiency, deficient › GABAtransaminase
- Deficiency, deficient › GABA-T
- Deficiency, deficient › succinic semialdehyde dehydrogenase
- Disorder › gamma aminobutyric acidmetabolism (of)
Inclusion terms
Alternative wording in documentation that is classified to E72.81.
- 4-hydroxybutyric aciduria
- Disorders of GABA metabolism
- GABA metabolic defect
- GABA transaminase deficiency
- GABA-T deficiency
- Gamma-hydroxybutyric aciduria
- SSADHD
- Succinic semialdehyde dehydrogenase deficiency
Excludes1 — never code together — inherited from Chapter 4
The conditions below can never be reported together with E72.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Excludes1 — never code together — inherited from E70-E88
The conditions below can never be reported together with E72.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from E72
The conditions below can never be reported together with E72.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes2 — not included here — inherited from E70-E88
The conditions below are not part of E72.81, but a patient may have both at the same time. When documentation supports it, E72.81 and the excluded code may both be reported.
- Ehlers-Danlos syndromes (Q79.6-)
How long has E72.81 existed?
E72.81 first appears in FY2019.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.