ICDcodes.org
FY2027

E72.3 — Disorders of lysine and hydroxylysine metabolism

BillableCC

Is E72.3 billable?

Yes — E72.3 is billable for FY2027. E72.3 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E72.3 may be submitted for encounters from October 1, 2026 through September 30, 2027.

E72.3 at a glance

CodeE72.3
DescriptionDisorders of lysine and hydroxylysine metabolism
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Which MS-DRGs does E72.3 group to?

E72.3 sits in MDC 10 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 642Inborn and Other Disorders of Metabolismmedical

As a secondary diagnosis, E72.3 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.

How is E72.3 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to E72.3. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Glutaric aciduria
  • Hydroxylysinemia
  • Hyperlysinemia
  • Lysine and hydroxylysine metabolism disorder
  • Saccharopinuria
  • Acidemia › pipecolic
  • Aciduria › glutaric
  • Disorder › lysine and hydroxylysine metabolism (of)
  • Hyperaminoaciduria › lysine
  • Intolerance › lysine
  • Disturbance › metabolism › hydroxylysine (s)
  • Disturbance › metabolism › lysine (s)

Excludes1 — never code together

The conditions below can never be reported together with E72.3 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

Inclusion terms

Alternative wording in documentation that is classified to E72.3.

  • Glutaric aciduria NOS
  • Glutaric aciduria (type I)
  • Hydroxylysinemia
  • Hyperlysinemia

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E72.3 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E70-E88

The conditions below can never be reported together with E72.3 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)

Excludes1 — never code together — inherited from E72

The conditions below can never be reported together with E72.3 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Excludes2 — not included here — inherited from E70-E88

The conditions below are not part of E72.3, but a patient may have both at the same time. When documentation supports it, E72.3 and the excluded code may both be reported.

  • Ehlers-Danlos syndromes (Q79.6-)

How long has E72.3 existed?

E72.3 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which codes are confused with E72.3?

ICD-10-CM declares these codes mutually exclusive with E72.3 — exactly one of each pair can be correct for a given encounter.

Which conditions are coded to E72.3?

What other codes are in the E72 family? (7)