ICDcodes.org
FY2027

E72.538Other specified primary hyperoxaluria

BillableUnspecifiedCC

Is E72.538 billable?

Yes, but E72.538 is an unspecified code. E72.538 is a valid, billable ICD-10-CM code for encounters from October 1, 2026 through September 30, 2027. However, E72.538 is an unspecified or catch-all code. Payers apply additional scrutiny to unspecified codes and many deny them when the medical record supports a more specific option, so check the documentation before selecting E72.538 — the more specific alternatives are listed below.

More specific alternatives

E72.538 at a glance

CodeE72.538
DescriptionOther specified primary hyperoxaluria
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Which MS-DRGs does E72.538 group to?

E72.538 sits in MDC 10 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 642Inborn and Other Disorders of Metabolismmedical

As a secondary diagnosis, E72.538 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.

How is E72.538 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to E72.538. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Disorderglycine metabolismhyperoxaluriaprimaryspecified type NEC (of)
  • Disorderglycine metabolismhyperoxaluriaprimarytype 2 (of)
  • Disorderglycine metabolismhyperoxaluriaprimarytype 3 (of)

Inclusion terms

Alternative wording in documentation that is classified to E72.538.

  • Primary hyperoxaluria, type 2
  • Primary hyperoxaluria, type 3

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E72.538 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E70-E88

The conditions below can never be reported together with E72.538 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)

Excludes1 — never code together — inherited from E72

The conditions below can never be reported together with E72.538 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • disorders of:
  • aromatic amino-acid metabolism (E70.-)
  • branched-chain amino-acid metabolism (E71.0-E71.2)
  • fatty-acid metabolism (E71.3)
  • purine and pyrimidine metabolism (E79.-)
  • gout (M1A.-, M10.-)

Excludes1 — never code together — inherited from E72.53

The conditions below can never be reported together with E72.538 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

Excludes2 — not included here — inherited from E70-E88

The conditions below are not part of E72.538, but a patient may have both at the same time. When documentation supports it, E72.538 and the excluded code may both be reported.

  • Ehlers-Danlos syndromes (Q79.6-)

How long has E72.538 existed?

E72.538 first appears in FY2026.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

What other codes are in the E72.53 family? (2)