ICDcodes.org
FY2027

E22Hyperfunction of pituitary gland

Not billable

Is E22 billable?

No — E22 is a non-billable header code. E22 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 5 billable codes beneath E22.

E22 at a glance

CodeE22
DescriptionHyperfunction of pituitary gland
BillableNo — header code
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Excludes1 — never code together

The conditions below can never be reported together with E22 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • Cushing's syndrome (E24.-)
  • Nelson's syndrome (E24.1)
  • overproduction of ACTH not associated with Cushing's disease (E27.0)
  • overproduction of pituitary ACTH (E24.0)
  • overproduction of thyroid-stimulating hormone (E05.8-)

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E22 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E20-E35

The conditions below can never be reported together with E22 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

What codes fall under E22? (5)

How long has E22 existed?

E22 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which codes are confused with E22?

ICD-10-CM declares these codes mutually exclusive with E22 — exactly one of each pair can be correct for a given encounter.