E22.1 — Hyperprolactinemia
Is E22.1 billable?
Yes — E22.1 is billable for FY2027. E22.1 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E22.1 may be submitted for encounters from October 1, 2026 through September 30, 2027.
E22.1 at a glance
| Code | E22.1 |
|---|---|
| Description | Hyperprolactinemia |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does E22.1 group to?
E22.1 sits in MDC 10 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 643Endocrine Disorders with MCCmedical
- 644Endocrine Disorders with CCmedical
- 645Endocrine Disorders without CC/MCCmedical
As a secondary diagnosis, E22.1 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is E22.1 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to E22.1. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Hyperprolactinemia
Use additional code
Report an additional code alongside E22.1 to fully describe the condition. E22.1 is sequenced first.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Excludes1 — never code together — inherited from Chapter 4
The conditions below can never be reported together with E22.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Excludes1 — never code together — inherited from E20-E35
The conditions below can never be reported together with E22.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from E22
The conditions below can never be reported together with E22.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
How long has E22.1 existed?
E22.1 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.