ICDcodes.org
FY2027

E22.9Hyperfunction of pituitary gland, unspecified

BillableUnspecifiedCC

Is E22.9 billable?

Yes, but E22.9 is an unspecified code. E22.9 is a valid, billable ICD-10-CM code for encounters from October 1, 2026 through September 30, 2027. However, E22.9 is an unspecified or catch-all code. Payers apply additional scrutiny to unspecified codes and many deny them when the medical record supports a more specific option, so check the documentation before selecting E22.9 — the more specific alternatives are listed below.

E22.9 at a glance

CodeE22.9
DescriptionHyperfunction of pituitary gland, unspecified
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Which MS-DRGs does E22.9 group to?

E22.9 sits in MDC 10 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 643Endocrine Disorders with MCCmedical
  • 644Endocrine Disorders with CCmedical
  • 645Endocrine Disorders without CC/MCCmedical

As a secondary diagnosis, E22.9 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.

How is E22.9 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to E22.9. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Hyperpituitarism
  • Hyperfunctionpituitary
  • Hypersecretionhormonepituitary
  • Increase, increasedfunctionpituitary

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E22.9 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E20-E35

The conditions below can never be reported together with E22.9 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

Excludes1 — never code together — inherited from E22

The conditions below can never be reported together with E22.9 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • Cushing's syndrome (E24.-)
  • Nelson's syndrome (E24.1)
  • overproduction of ACTH not associated with Cushing's disease (E27.0)
  • overproduction of pituitary ACTH (E24.0)
  • overproduction of thyroid-stimulating hormone (E05.8-)

How long has E22.9 existed?

E22.9 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

What other codes are in the E22 family? (4)