ICDcodes.org
FY2027

E88.A — Wasting disease (syndrome) due to underlying condition

Billable

Is E88.A billable?

Yes — E88.A is billable for FY2027. E88.A is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E88.A may be submitted for encounters from October 1, 2026 through September 30, 2027.

E88.A at a glance

CodeE88.A
DescriptionWasting disease (syndrome) due to underlying condition
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

What Medicare edits apply to E88.A?

The Medicare Code Editor screens inpatient claims before they are grouped. These edits name E88.A directly.

Cannot be a principal diagnosis — MCE edit 9

CMS will reject this code as the principal diagnosis on an inpatient claim. It describes something other than the condition chiefly responsible for the admission.

Which MS-DRGs does E88.A group to?

E88.A sits in MDC 10 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 642Inborn and Other Disorders of Metabolismmedical

How is E88.A listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to E88.A. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Disease, diseased › wasting NEC
  • Syndrome › wastingdue to underlying condition
  • Wasting › disease
  • Cachexia › due to › malnutrition
  • Cachexia › due to › underlying condition
  • Disease, diseased › wasting NEC › due to › underlying condition
  • Wasting › disease › due to › underlying condition

Excludes1 — never code together

The conditions below can never be reported together with E88.A on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • cachexia NOS (R64)
  • nutritional marasmus (E41)

Code first

The underlying condition below must be sequenced before E88.A. E88.A describes a manifestation and cannot be the principal or first-listed diagnosis.

  • underlying condition

Excludes2 — not included here

The conditions below are not part of E88.A, but a patient may have both at the same time. When documentation supports it, E88.A and the excluded code may both be reported.

Inclusion terms

Alternative wording in documentation that is classified to E88.A.

  • Cachexia due to underlying condition

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E88.A on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E70-E88

The conditions below can never be reported together with E88.A on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)

Excludes1 — never code together — inherited from E88

The conditions below can never be reported together with E88.A on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • histiocytosis X (chronic) (C96.6)

Use additional code — inherited from E88

Report an additional code alongside E88.A to fully describe the condition. E88.A is sequenced first.

  • codes for associated conditions

Excludes2 — not included here — inherited from E70-E88

The conditions below are not part of E88.A, but a patient may have both at the same time. When documentation supports it, E88.A and the excluded code may both be reported.

  • Ehlers-Danlos syndromes (Q79.6-)

How long has E88.A existed?

E88.A first appears in FY2024.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which codes are confused with E88.A?

ICD-10-CM declares these codes mutually exclusive with E88.A — exactly one of each pair can be correct for a given encounter.

Which conditions are coded to E88.A?

What other codes are in the E88 family? (7)