Excludes1 pair

E41 vs E88.A

E41 and E88.A are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on E88.A
nutritional marasmus (E41)
E41

Nutritional marasmus

Billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E40-E46
Use when the record says
  • Severe malnutrition with marasmus
Indexed under
  • Athrepsia
  • Marasmus
  • Pedatrophia
  • Atrophy, atrophic › infantile
  • Marasmus › due to malnutrition
E88.A

Wasting disease (syndrome) due to underlying condition

Billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E70-E88
Use when the record says
  • Cachexia due to underlying condition
Indexed under
  • Disease, diseased › wasting NEC
  • Syndrome › wasting due to underlying condition (syndrome)
  • Wasting › disease (syndrome)
  • Cachexia › due to › malnutrition
  • Cachexia › due to › underlying condition

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027