ICDcodes.org
FY2027

E75.249Niemann-Pick disease, unspecified

BillableUnspecified

Is E75.249 billable?

Yes, but E75.249 is an unspecified code. E75.249 is a valid, billable ICD-10-CM code for encounters from October 1, 2026 through September 30, 2027. However, E75.249 is an unspecified or catch-all code. Payers apply additional scrutiny to unspecified codes and many deny them when the medical record supports a more specific option, so check the documentation before selecting E75.249 — the more specific alternatives are listed below.

E75.249 at a glance

CodeE75.249
DescriptionNiemann-Pick disease, unspecified
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Which MS-DRGs does E75.249 group to?

E75.249 sits in MDC 10 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 642Inborn and Other Disorders of Metabolismmedical

How is E75.249 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to E75.249. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Niemann-Pick disease or syndrome
  • Deficiency, deficientacid sphingomyelinase
  • Degeneration, degenerativebraininNiemann-Pick disease

Inclusion terms

Alternative wording in documentation that is classified to E75.249.

  • Acid sphingomyelinase deficiency (ASMD) NOS

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E75.249 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E70-E88

The conditions below can never be reported together with E75.249 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)

Excludes1 — never code together — inherited from E75

The conditions below can never be reported together with E75.249 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • mucolipidosis, types I-III (E77.0-E77.1)
  • Refsum's disease (G60.1)

Excludes1 — never code together — inherited from E75.2

The conditions below can never be reported together with E75.249 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • adrenoleukodystrophy [Addison-Schilder] (E71.528)

Excludes2 — not included here — inherited from E70-E88

The conditions below are not part of E75.249, but a patient may have both at the same time. When documentation supports it, E75.249 and the excluded code may both be reported.

  • Ehlers-Danlos syndromes (Q79.6-)

How long has E75.249 existed?

E75.249 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which conditions are coded to E75.249?

What other codes are in the E75.24 family? (6)