ICD-10 Code for Amyloidosis
Also indexed as (generalized) (primary)
The ICD-10-CM code for amyloidosis is E85.9 — Amyloidosis, unspecified. This is the code the Alphabetic Index gives for amyloidosis with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).
E85.9 is billable but unspecified. If the documentation names a type, site or cause, one of the more specific codes below is likely expected.
Which amyloidosis code should you use?
The Alphabetic Index lists 13 codes under Amyloidosis. Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.
By type
| with lung involvement | E85.4 | Organ-limited amyloidosis | |
| familial | E85.2 | Heredofamilial amyloidosis, unspecified | |
| genetic | E85.2 | Heredofamilial amyloidosis, unspecified | |
| heart | E85.4 | Organ-limited amyloidosis | |
| hemodialysis-associated | E85.3 | Secondary systemic amyloidosis | |
| light chain | E85.81 | Light chain (AL) amyloidosis | |
| liver | E85.4 | Organ-limited amyloidosis | |
| localized | E85.4 | Organ-limited amyloidosis | |
| neuropathic heredofamilial | E85.1 | Neuropathic heredofamilial amyloidosis | |
| non-neuropathic heredofamilial | E85.0 | Non-neuropathic heredofamilial amyloidosis | |
| organ limited | E85.4 | Organ-limited amyloidosis | |
| Portuguese | E85.1 | Neuropathic heredofamilial amyloidosis | |
| pulmonary | E85.4 | Organ-limited amyloidosis | |
| secondary systemic | E85.3 | Secondary systemic amyloidosis | |
| senile systemic | E85.82 | Wild-type transthyretin-related (ATTR) amyloidosis | |
| skin | E85.4 | Organ-limited amyloidosis | |
| specified NEC | E85.89 | Other amyloidosis | |
| subglottic | E85.4 | Organ-limited amyloidosis | |
| wild-type transthyretin-related | E85.82 | Wild-type transthyretin-related (ATTR) amyloidosis |
Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources