ICDcodes.org
FY2027

E85.9Amyloidosis, unspecified

BillableUnspecifiedCC

Is E85.9 billable?

Yes, but E85.9 is an unspecified code. E85.9 is a valid, billable ICD-10-CM code for encounters from October 1, 2026 through September 30, 2027. However, E85.9 is an unspecified or catch-all code. Payers apply additional scrutiny to unspecified codes and many deny them when the medical record supports a more specific option, so check the documentation before selecting E85.9 — the more specific alternatives are listed below.

E85.9 at a glance

CodeE85.9
DescriptionAmyloidosis, unspecified
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Which MS-DRGs does E85.9 group to?

E85.9 sits in MDC 08 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 545Connective Tissue Disorders with MCCmedical
  • 546Connective Tissue Disorders with CCmedical
  • 547Connective Tissue Disorders without CC/MCCmedical

As a secondary diagnosis, E85.9 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.

How is E85.9 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to E85.9. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Amyloidosis (generalized) (primary)
  • Degeneration, degenerativeamyloid

Excludes1 — never code together — inherited from Chapter 4

The conditions below can never be reported together with E85.9 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • transitory endocrine and metabolic disorders specific to newborn (P70-P74)

Excludes1 — never code together — inherited from E70-E88

The conditions below can never be reported together with E85.9 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • androgen insensitivity syndrome (E34.5-)
  • congenital adrenal hyperplasia (E25.0)
  • hemolytic anemias attributable to enzyme disorders (D55.-)
  • Marfan syndrome (Q87.4-)
  • 5-alpha-reductase deficiency (E29.1)

Excludes2 — not included here — inherited from E70-E88

The conditions below are not part of E85.9, but a patient may have both at the same time. When documentation supports it, E85.9 and the excluded code may both be reported.

  • Ehlers-Danlos syndromes (Q79.6-)

Excludes2 — not included here — inherited from E85

The conditions below are not part of E85.9, but a patient may have both at the same time. When documentation supports it, E85.9 and the excluded code may both be reported.

How long has E85.9 existed?

E85.9 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which conditions are coded to E85.9?

What other codes are in the E85 family? (6)