Neoplasms
Chapter 2 of the ICD-10-CM Tabular List covers C00-D49 and contains 2,181 codes across 141 categories, of which 1,730 are billable for FY2027.
Note
- Functional activity
- All neoplasms are classified in this chapter, whether they are functionally active or not. An additional code from Chapter 4 may be used, to identify functional activity associated with any neoplasm.
- Morphology [Histology]
- Chapter 2 classifies neoplasms primarily by site (topography), with broad groupings for behavior, malignant, in situ, benign, etc. The Table of Neoplasms should be used to identify the correct topography code. In a few cases, such as for malignant melanoma and certain neuroendocrine tumors, the morphology (histologic type) is included in the category and codes.
- Primary malignant neoplasms overlapping site boundaries
- A primary malignant neoplasm that overlaps two or more contiguous (next to each other) sites should be classified to the subcategory/code .8 ('overlapping lesion'), unless the combination is specifically indexed elsewhere. For multiple neoplasms of the same site that are not contiguous, such as tumors in different quadrants of the same breast, codes for each site should be assigned.
- Malignant neoplasm of ectopic tissue
- Malignant neoplasms of ectopic tissue are to be coded to the site mentioned, e.g., ectopic pancreatic malignant neoplasms are coded to pancreas, unspecified (C25.9).
C00-C14 — Malignant neoplasms of lip, oral cavity and pharynx
- C00Malignant neoplasm of lip
- C01Malignant neoplasm of base of tongue
- C02Malignant neoplasm of other and unspecified parts of tongue
- C03Malignant neoplasm of gum
- C04Malignant neoplasm of floor of mouth
- C05Malignant neoplasm of palate
- C06Malignant neoplasm of other and unspecified parts of mouth
- C07Malignant neoplasm of parotid gland
- C08Malignant neoplasm of other and unspecified major salivary glands
- C09Malignant neoplasm of tonsil
- C10Malignant neoplasm of oropharynx
- C11Malignant neoplasm of nasopharynx
- C12Malignant neoplasm of pyriform sinus
- C13Malignant neoplasm of hypopharynx
- C14Malignant neoplasm of other and ill-defined sites in the lip, oral cavity and pharynx
C15-C26 — Malignant neoplasms of digestive organs
- C15Malignant neoplasm of esophagus
- C16Malignant neoplasm of stomach
- C17Malignant neoplasm of small intestine
- C18Malignant neoplasm of colon
- C19Malignant neoplasm of rectosigmoid junction
- C20Malignant neoplasm of rectum
- C21Malignant neoplasm of anus and anal canal
- C22Malignant neoplasm of liver and intrahepatic bile ducts
- C23Malignant neoplasm of gallbladder
- C24Malignant neoplasm of other and unspecified parts of biliary tract
- C25Malignant neoplasm of pancreas
- C26Malignant neoplasm of other and ill-defined digestive organs
C30-C39 — Malignant neoplasms of respiratory and intrathoracic organs
- C30Malignant neoplasm of nasal cavity and middle ear
- C31Malignant neoplasm of accessory sinuses
- C32Malignant neoplasm of larynx
- C33Malignant neoplasm of trachea
- C34Malignant neoplasm of bronchus and lung
- C37Malignant neoplasm of thymus
- C38Malignant neoplasm of heart, mediastinum and pleura
- C39Malignant neoplasm of other and ill-defined sites in the respiratory system and intrathoracic organs
C40-C41 — Malignant neoplasms of bone and articular cartilage
C43-C44 — Melanoma and other malignant neoplasms of skin
C45-C49 — Malignant neoplasms of mesothelial and soft tissue
C50 — Malignant neoplasms of breast (C50)
C51-C58 — Malignant neoplasms of female genital organs
- C51Malignant neoplasm of vulva
- C52Malignant neoplasm of vagina
- C53Malignant neoplasm of cervix uteri
- C54Malignant neoplasm of corpus uteri
- C55Malignant neoplasm of uterus, part unspecified
- C56Malignant neoplasm of ovary
- C57Malignant neoplasm of other and unspecified female genital organs
- C58Malignant neoplasm of placenta
C60-C63 — Malignant neoplasms of male genital organs
C64-C68 — Malignant neoplasms of urinary tract
C69-C72 — Malignant neoplasms of eye, brain and other parts of central nervous system
C73-C75 — Malignant neoplasms of thyroid and other endocrine glands
C7A — Malignant neuroendocrine tumors (C7A)
C7B — Secondary neuroendocrine tumors (C7B)
C76-C80 — Malignant neoplasms of ill-defined, other secondary and unspecified sites
C81-C96 — Malignant neoplasms of lymphoid, hematopoietic and related tissue
- C81Hodgkin lymphoma
- C82Follicular lymphoma
- C83Non-follicular lymphoma
- C84Mature T/NK-cell lymphomas
- C85Other specified and unspecified types of non-Hodgkin lymphoma
- C86Other specified types of T/NK-cell lymphoma
- C88Malignant immunoproliferative diseases and certain other B-cell lymphomas
- C90Multiple myeloma and malignant plasma cell neoplasms
- C91Lymphoid leukemia
- C92Myeloid leukemia
- C93Monocytic leukemia
- C94Other leukemias of specified cell type
- C95Leukemia of unspecified cell type
- C96Other and unspecified malignant neoplasms of lymphoid, hematopoietic and related tissue
D00-D09 — In situ neoplasms
- D00Carcinoma in situ of oral cavity, esophagus and stomach
- D01Carcinoma in situ of other and unspecified digestive organs
- D02Carcinoma in situ of middle ear and respiratory system
- D03Melanoma in situ
- D04Carcinoma in situ of skin
- D05Carcinoma in situ of breast
- D06Carcinoma in situ of cervix uteri
- D07Carcinoma in situ of other and unspecified genital organs
- D09Carcinoma in situ of other and unspecified sites
D10-D36 — Benign neoplasms, except benign neuroendocrine tumors
- D10Benign neoplasm of mouth and pharynx
- D11Benign neoplasm of major salivary glands
- D12Benign neoplasm of colon, rectum, anus and anal canal
- D13Benign neoplasm of other and ill-defined parts of digestive system
- D14Benign neoplasm of middle ear and respiratory system
- D15Benign neoplasm of other and unspecified intrathoracic organs
- D16Benign neoplasm of bone and articular cartilage
- D17Benign lipomatous neoplasm
- D18Hemangioma and lymphangioma, any site
- D19Benign neoplasm of mesothelial tissue
- D20Benign neoplasm of soft tissue of retroperitoneum and peritoneum
- D21Other benign neoplasms of connective and other soft tissue
- D22Melanocytic nevi
- D23Other benign neoplasms of skin
- D24Benign neoplasm of breast
- D25Leiomyoma of uterus
- D26Other benign neoplasms of uterus
- D27Benign neoplasm of ovary
- D28Benign neoplasm of other and unspecified female genital organs
- D29Benign neoplasm of male genital organs
- D30Benign neoplasm of urinary organs
- D31Benign neoplasm of eye and adnexa
- D32Benign neoplasm of meninges
- D33Benign neoplasm of brain and other parts of central nervous system
- D34Benign neoplasm of thyroid gland
- D35Benign neoplasm of other and unspecified endocrine glands
- D36Benign neoplasm of other and unspecified sites
D3A — Benign neuroendocrine tumors (D3A)
D37-D48 — Neoplasms of uncertain behavior, polycythemia vera and myelodysplastic syndromes
- D37Neoplasm of uncertain behavior of oral cavity and digestive organs
- D38Neoplasm of uncertain behavior of middle ear and respiratory and intrathoracic organs
- D39Neoplasm of uncertain behavior of female genital organs
- D40Neoplasm of uncertain behavior of male genital organs
- D41Neoplasm of uncertain behavior of urinary organs
- D42Neoplasm of uncertain behavior of meninges
- D43Neoplasm of uncertain behavior of brain and central nervous system
- D44Neoplasm of uncertain behavior of endocrine glands
- D45Polycythemia vera
- D46Myelodysplastic syndromes
- D47Other neoplasms of uncertain behavior of lymphoid, hematopoietic and related tissue
- D48Neoplasm of uncertain behavior of other and unspecified sites