D46 — Myelodysplastic syndromes
Is D46 billable?
No — D46 is a non-billable header code. D46 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 11 billable codes beneath D46.
Billable codes under this header
- D46.0Refractory anemia without ring sideroblasts, so stated
- D46.1Refractory anemia with ring sideroblasts
- D46.ARefractory cytopenia with multilineage dysplasia
- D46.BRefractory cytopenia with multilineage dysplasia and ring sideroblasts
- D46.CMyelodysplastic syndrome with isolated del(5q) chromosomal abnormality
- D46.4Refractory anemia, unspecified
- D46.ZOther myelodysplastic syndromes
- D46.9Myelodysplastic syndrome, unspecified
- D46.20Refractory anemia with excess of blasts, unspecified
- D46.21Refractory anemia with excess of blasts 1
- D46.22Refractory anemia with excess of blasts 2
D46 at a glance
| Code | D46 |
|---|---|
| Description | Myelodysplastic syndromes |
| Billable | No — header code |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Use additional code
Report an additional code alongside D46 to fully describe the condition. D46 is sequenced first.
- code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
Excludes2 — not included here
The conditions below are not part of D46, but a patient may have both at the same time. When documentation supports it, D46 and the excluded code may both be reported.
- drug-induced aplastic anemia (D61.1)
Excludes1 — never code together — inherited from D37-D48
The conditions below can never be reported together with D46 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- neoplasms of unspecified behavior (D49.-)
What codes fall under D46? (9)
- D46.0Refractory anemia without ring sideroblasts, so stated
- D46.1Refractory anemia with ring sideroblasts
- D46.2Refractory anemia with excess of blasts [RAEB]not billable
- D46.ARefractory cytopenia with multilineage dysplasia
- D46.BRefractory cytopenia with multilineage dysplasia and ring sideroblasts
- D46.CMyelodysplastic syndrome with isolated del(5q) chromosomal abnormality
- D46.4Refractory anemia, unspecified
- D46.ZOther myelodysplastic syndromes
- D46.9Myelodysplastic syndrome, unspecified
How long has D46 existed?
D46 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
Which codes are confused with D46?
ICD-10-CM declares these codes mutually exclusive with D46 — exactly one of each pair can be correct for a given encounter.