D80 — Immunodeficiency with predominantly antibody defects
Is D80 billable?
No — D80 is a non-billable header code. D80 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 10 billable codes beneath D80.
Billable codes under this header
- D80.0Hereditary hypogammaglobulinemia
- D80.1Nonfamilial hypogammaglobulinemia
- D80.2Selective deficiency of immunoglobulin A [IgA]
- D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
- D80.4Selective deficiency of immunoglobulin M [IgM]
- D80.5Immunodeficiency with increased immunoglobulin M [IgM]
- D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
- D80.7Transient hypogammaglobulinemia of infancy
- D80.8Other immunodeficiencies with predominantly antibody defects
- D80.9Immunodeficiency with predominantly antibody defects, unspecified
D80 at a glance
| Code | D80 |
|---|---|
| Description | Immunodeficiency with predominantly antibody defects |
| Billable | No — header code |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Excludes1 — never code together — inherited from D80-D89
The conditions below can never be reported together with D80 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes2 — not included here — inherited from Chapter 3
The conditions below are not part of D80, but a patient may have both at the same time. When documentation supports it, D80 and the excluded code may both be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Excludes2 — not included here — inherited from D80-D89
The conditions below are not part of D80, but a patient may have both at the same time. When documentation supports it, D80 and the excluded code may both be reported.
- human immunodeficiency virus [HIV] disease (B20)
What codes fall under D80? (10)
- D80.0Hereditary hypogammaglobulinemia
- D80.1Nonfamilial hypogammaglobulinemia
- D80.2Selective deficiency of immunoglobulin A [IgA]
- D80.3Selective deficiency of immunoglobulin G [IgG] subclasses
- D80.4Selective deficiency of immunoglobulin M [IgM]
- D80.5Immunodeficiency with increased immunoglobulin M [IgM]
- D80.6Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
- D80.7Transient hypogammaglobulinemia of infancy
- D80.8Other immunodeficiencies with predominantly antibody defects
- D80.9Immunodeficiency with predominantly antibody defects, unspecified
How long has D80 existed?
D80 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.