ICDcodes.org
FY2027

D80.1 — Nonfamilial hypogammaglobulinemia

BillableCC

Is D80.1 billable?

Yes — D80.1 is billable for FY2027. D80.1 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. D80.1 may be submitted for encounters from October 1, 2026 through September 30, 2027.

D80.1 at a glance

CodeD80.1
DescriptionNonfamilial hypogammaglobulinemia
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Which MS-DRGs does D80.1 group to?

D80.1 sits in MDC 16 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 814Reticuloendothelial and Immunity Disorders with MCCmedical
  • 815Reticuloendothelial and Immunity Disorders with CCmedical
  • 816Reticuloendothelial and Immunity Disorders without CC/MCCmedical

As a secondary diagnosis, D80.1 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.

How is D80.1 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to D80.1. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Agammaglobulinemia (acquired (secondary)) (nonfamilial)
  • Hypogammaglobulinemia
  • Absence › gamma globulin in blood (of) (organ or part) (complete or partial)
  • Agammaglobulinemia › common variable (acquired (secondary)) (nonfamilial)
  • Deficiency, deficient › gammaglobulin in blood
  • Hypogammaglobulinemia › nonfamilial
  • Agammaglobulinemia › with › immunoglobulin-bearing B-lymphocytes (acquired (secondary)) (nonfamilial)
  • Arthritis, arthritic › in › hypogammaglobulinemia (acute) (chronic) (nonpyogenic) (subacute)
  • Syndrome › antibody deficiency › agammaglobulinemic
  • Syndrome › antibody deficiency › hypogammaglobulinemic
  • Disease, diseased › connective tissue, systemic › in › hypogammaglobulinemia

Inclusion terms

Alternative wording in documentation that is classified to D80.1.

  • Agammaglobulinemia with immunoglobulin-bearing B-lymphocytes
  • Common variable agammaglobulinemia [CVAgamma]
  • Hypogammaglobulinemia NOS

Excludes1 — never code together — inherited from D80-D89

The conditions below can never be reported together with D80.1 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • autoimmune disease (systemic) NOS (M35.9)
  • functional disorders of polymorphonuclear neutrophils (D71-)

Excludes2 — not included here — inherited from Chapter 3

The conditions below are not part of D80.1, but a patient may have both at the same time. When documentation supports it, D80.1 and the excluded code may both be reported.

  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

Excludes2 — not included here — inherited from D80-D89

The conditions below are not part of D80.1, but a patient may have both at the same time. When documentation supports it, D80.1 and the excluded code may both be reported.

  • human immunodeficiency virus [HIV] disease (B20)

How long has D80.1 existed?

D80.1 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which conditions are coded to D80.1?

What other codes are in the D80 family? (9)