D59.2 — Drug-induced nonautoimmune hemolytic anemia

BillableCC

Is D59.2 billable?

Yes — D59.2 is billable for FY2027. D59.2 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. D59.2 may be submitted for encounters from October 1, 2026 through September 30, 2027.

D59.2 at a glance

Code	D59.2
Description	Drug-induced nonautoimmune hemolytic anemia
Billable	Yes
Code set	ICD-10-CM FY2027
Valid for encounters	October 1, 2026 – September 30, 2027

Which MS-DRGs does D59.2 group to?

D59.2 sits in MDC 15 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

791Prematurity with Major Problemsmedical

As a secondary diagnosis, D59.2 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.

How is D59.2 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to D59.2. They show the wording a clinician may have documented, which often differs from the Tabular description.

Anemia › enzyme-deficiency, drug-induced (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
Nonautoimmune hemolytic anemia › drug-induced
Disease, diseased › nonautoimmune hemolytic › drug-induced
Anemia › deficiency › enzyme › drug-induced (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
Anemia › hemolytic › due to › drugs (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
Anemia › hemolytic › nonautoimmune › drug-induced (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
Anemia › hemolytic › due to › enzyme disorder › drug-induced (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)

Use additional code

Report an additional code alongside D59.2 to fully describe the condition. D59.2 is sequenced first.

code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion terms

Alternative wording in documentation that is classified to D59.2.

Drug-induced enzyme deficiency anemia

Excludes2 — not included here — inherited from Chapter 3

The conditions below are not part of D59.2, but a patient may have both at the same time. When documentation supports it, D59.2 and the excluded code may both be reported.

autoimmune disease (systemic) NOS (M35.9)
certain conditions originating in the perinatal period (P00-P96)
complications of pregnancy, childbirth and the puerperium (O00-O9A)
congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
endocrine, nutritional and metabolic diseases (E00-E88)
human immunodeficiency virus [HIV] disease (B20)
injury, poisoning and certain other consequences of external causes (S00-T88)
neoplasms (C00-D49)
symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

How long has D59.2 existed?

D59.2 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which codes are confused with D59.2?

ICD-10-CM declares these codes mutually exclusive with D59.2 — exactly one of each pair can be correct for a given encounter.

vs D55Anemia due to enzyme disorders