D55 vs D59.2
D55 and D59.2 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.
The official note, declared on D55
drug-induced enzyme deficiency anemia (D59.2)
D55
Anemia due to enzyme disorders
Not billable
- Chapter 3
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Section
- D55-D59
D59.2
Drug-induced nonautoimmune hemolytic anemia
Billable
- Chapter 3
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Section
- D55-D59
Use when the record says
- Drug-induced enzyme deficiency anemia
Indexed under
- Anemia › enzyme-deficiency, drug-induced (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- Nonautoimmune hemolytic anemia › drug-induced
- Disease, diseased › nonautoimmune hemolytic › drug-induced
- Anemia › deficiency › enzyme › drug-induced (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- Anemia › hemolytic › due to › drugs (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027