ICDcodes.org
FY2027

D57.439 — Sickle-cell thalassemia beta zero with crisis, unspecified

BillableUnspecifiedMCC

Is D57.439 billable?

Yes, but D57.439 is an unspecified code. D57.439 is a valid, billable ICD-10-CM code for encounters from October 1, 2026 through September 30, 2027. However, D57.439 is an unspecified or catch-all code. Payers apply additional scrutiny to unspecified codes and many deny them when the medical record supports a more specific option, so check the documentation before selecting D57.439 — the more specific alternatives are listed below.

D57.439 at a glance

CodeD57.439
DescriptionSickle-cell thalassemia beta zero with crisis, unspecified
BillableYes
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

Which MS-DRGs does D57.439 group to?

D57.439 sits in MDC 15 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.

  • 791Prematurity with Major Problemsmedical

As a secondary diagnosis, D57.439 is a major complication or comorbidity (MCC), which can move a stay into a higher-paying DRG.

How is D57.439 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to D57.439. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Disease, diseased › hemoglobin or Hb › S or SS › beta zero › with › crisis
  • Disease, diseased › hemoglobin or Hb › S or SS › beta zero › with › pain
  • Disease, diseased › sickle-cell › thalassemia › beta zero › with › crisis
  • Disease, diseased › sickle-cell › thalassemia › beta zero › with › pain

Inclusion terms

Alternative wording in documentation that is classified to D57.439.

  • HbS-beta zero with other specified complication
  • Sickle-cell beta zero with crisis unspecified
  • Sickle-cell thalassemia beta zero with (painful) crisis NOS
  • Sickle-cell thalassemia beta zero with (vaso-occlusive) pain NOS

Excludes1 — never code together — inherited from D57

The conditions below can never be reported together with D57.439 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • other hemoglobinopathies (D58.-)

Use additional code — inherited from D57

Report an additional code alongside D57.439 to fully describe the condition. D57.439 is sequenced first.

  • code for any associated fever (R50.81)

Excludes2 — not included here — inherited from Chapter 3

The conditions below are not part of D57.439, but a patient may have both at the same time. When documentation supports it, D57.439 and the excluded code may both be reported.

  • autoimmune disease (systemic) NOS (M35.9)
  • certain conditions originating in the perinatal period (P00-P96)
  • complications of pregnancy, childbirth and the puerperium (O00-O9A)
  • congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
  • endocrine, nutritional and metabolic diseases (E00-E88)
  • human immunodeficiency virus [HIV] disease (B20)
  • injury, poisoning and certain other consequences of external causes (S00-T88)
  • neoplasms (C00-D49)
  • symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)

How long has D57.439 existed?

D57.439 first appears in FY2021 (FY2020 is not available, so it may have appeared then).

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

What other codes are in the D57.43 family? (5)