Excludes1 pair
C92.0- vs D46-
C92.0 and D46 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.
The official note, declared on C92.0
refractory anemia with excess of blasts not in transformation (D46.2-)
C92.0
Acute myeloblastic leukemia
Not billable
- Chapter 2
- Neoplasms
- Section
- C81-C96
Use when the record says
- Acute myeloblastic leukemia, minimal differentiation
- Acute myeloblastic leukemia (with maturation)
- Acute myeloblastic leukemia 1/ETO
- Acute myeloblastic leukemia M0
- Acute myeloblastic leukemia M1
- Acute myeloblastic leukemia M2
- Acute myeloblastic leukemia with t(8;21)
- Acute myeloblastic leukemia (without a FAB classification) NOS
Indexed under
- Leukemia, leukemic › acute myeloblastic (minimal differentiation) (with maturation)
- Leukemia, leukemic › acute myeloid, NOS
- Leukemia, leukemic › AML (1/ETO) (M0) (M1) (M2) (without a FAB classification)
- Myelosis › acute
- Leukemia, leukemic › myeloid › acute
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027