ICD-10 Code for Sepsis
Also indexed as (generalized) (unspecified organism)
The ICD-10-CM code for sepsis is A41.9 — Sepsis, unspecified organism. This is the code the Alphabetic Index gives for sepsis with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).
BillableUnspecified
A41.9 is billable but unspecified. If the documentation names a type, site or cause, one of the more specific codes below is likely expected.
Which sepsis code should you use?
The Alphabetic Index lists 79 codes under Sepsis. Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.
By type
| Acinetobacter baumannii | A41.54 | Sepsis due to Acinetobacter baumannii | |
| actinomycotic | A42.7 | Actinomycotic sepsis | |
| adrenal hemorrhage syndrome | A39.1 | Waterhouse-Friderichsen syndrome | |
| anaerobic | A41.4 | Sepsis due to anaerobes | |
| Bacillus anthracis | A22.7 | Anthrax sepsis | |
| Brucella | A23.9 | Brucellosis, unspecified | |
| candidal | B37.7 | Candidal sepsis | |
| Cronobacter | A41.59 | Other Gram-negative sepsis | |
| cryptogenic | A41.9 | Sepsis, unspecified organism | |
| due to device, implant or graft | T85.79 | Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts | not billable |
| during labor | O75.3 | Other infection during labor | |
| Enterococcus | A41.81 | Sepsis due to Enterococcus | |
| Erysipelothrix | A26.7 | Erysipelothrix sepsis | |
| Escherichia coli | A41.51 | Sepsis due to Escherichia coli [E. coli] | |
| extraintestinal yersiniosis | A28.2 | Extraintestinal yersiniosis | |
| gangrenous | A41.9 | Sepsis, unspecified organism | |
| gonococcal | A54.86 | Gonococcal sepsis | |
| Gram-negative | A41.50 | Gram-negative sepsis, unspecified | |
| Haemophilus influenzae | A41.3 | Sepsis due to Hemophilus influenzae | |
| herpesviral | B00.7 | Disseminated herpesviral disease | |
| intra-abdominal | K65.1 | Peritoneal abscess | |
| Listeria monocytogenes | A32.7 | Listerial sepsis | |
| malleus | A24.0 | Glanders | |
| melioidosis | A24.1 | Acute and fulminating melioidosis | |
| meningococcal | A39.4 | Meningococcemia, unspecified | |
| MRSA | A41.02 | Sepsis due to Methicillin resistant Staphylococcus aureus | |
| MSSA | A41.01 | Sepsis due to Methicillin susceptible Staphylococcus aureus | |
| newborn | P36.9 | Bacterial sepsis of newborn, unspecified | |
| other gram-negative | A41.59 | Other Gram-negative sepsis | |
| Pasteurella multocida | A28.0 | Pasteurellosis | |
| pelvic, puerperal, postpartum, childbirth | O85 | Puerperal sepsis | |
| postprocedural | T81.44 | Sepsis following a procedure | not billable |
| pneumococcal | A40.3 | Sepsis due to Streptococcus pneumoniae | |
| Pseudomonas | A41.52 | Sepsis due to Pseudomonas | |
| puerperal, postpartum, childbirth | O85 | Puerperal sepsis | |
| Salmonella | A02.1 | Salmonella sepsis | |
| Serratia | A41.53 | Sepsis due to Serratia | |
| severe | R65.20 | Severe sepsis without septic shock | |
| Shigella | A03.9 | Shigellosis, unspecified | |
| specified organism NEC | A41.89 | Other specified sepsis | |
| Staphylococcus, staphylococcal | A41.2 | Sepsis due to unspecified staphylococcus | |
| Streptococcus, streptococcal | A40.9 | Streptococcal sepsis, unspecified | |
| tracheostomy stoma | J95.02 | Infection of tracheostomy stoma | |
| tularemic | A21.7 | Generalized tularemia | |
| Yersinia pestis | A20.7 | Septicemic plague |
Sepsis with
Sepsis due to device, implant or graft
| arterial graft NEC | T82.7 | Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts | not billable |
| breast | T85.79 | Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts | not billable |
| catheter NEC | T85.79 | Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts | not billable |
| gastrointestinal | T85.79 | Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts | not billable |
| genital | T83.69 | Infection and inflammatory reaction due to other prosthetic device, implant and graft in genital tract | not billable |
| heart NEC | T82.7 | Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts | not billable |
| ocular | T85.79 | Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts | not billable |
| orthopedic NEC | T84.7 | Infection and inflammatory reaction due to other internal orthopedic prosthetic devices, implants and grafts | not billable |
| specified NEC | T85.79 | Infection and inflammatory reaction due to other internal prosthetic devices, implants and grafts | not billable |
| vascular | T82.7 | Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts | not billable |
| ventricular intracranialshunt | T85.730 | Infection and inflammatory reaction due to ventricular intracranial (communicating) shunt | not billable |
| catheter NEC › dialysis | T82.7 | Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts | not billable |
| catheter NEC › infusion NEC | T82.7 | Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts | not billable |
| catheter NEC › urethral indwelling | T83.511 | Infection and inflammatory reaction due to indwelling urethral catheter | not billable |
| catheter NEC › urinary | T83.518 | Infection and inflammatory reaction due to other urinary catheter | not billable |
| electronic › bone | T84.7 | Infection and inflammatory reaction due to other internal orthopedic prosthetic devices, implants and grafts | not billable |
| electronic › cardiac | T82.7 | Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts | not billable |
| electronic › nervous system | T85.738 | Infection and inflammatory reaction due to other nervous system device, implant or graft | not billable |
| electronic › urinary | T83.590 | Infection and inflammatory reaction due to implanted urinary neurostimulation device | not billable |
| gastrointestinal › neurostimulator electrode | T85.732 | Infection and inflammatory reaction due to implanted electronic neurostimulator of peripheral nerve, electrode (lead) | not billable |
| heart NEC › valve | T82.6 | Infection and inflammatory reaction due to cardiac valve prosthesis | not billable |
| catheter NEC › dialysis › intraperitoneal | T85.71 | Infection and inflammatory reaction due to peritoneal dialysis catheter | not billable |
| catheter NEC › infusion NEC › spinal | T85.735 | Infection and inflammatory reaction due to cranial or spinal infusion catheter | not billable |
| electronic › nervous system › brain | T85.731 | Infection and inflammatory reaction due to implanted electronic neurostimulator of brain, electrode (lead) | not billable |
| electronic › nervous system › neurostimulator generator | T85.734 | Infection and inflammatory reaction due to implanted electronic neurostimulator, generator | not billable |
| electronic › nervous system › peripheral nerve | T85.732 | Infection and inflammatory reaction due to implanted electronic neurostimulator of peripheral nerve, electrode (lead) | not billable |
| electronic › nervous system › spinal cord | T85.733 | Infection and inflammatory reaction due to implanted electronic neurostimulator of spinal cord, electrode (lead) | not billable |
| heart NEC › valve › graft | T82.7 | Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts | not billable |
Sepsis following
| abortion | O08.0 | Genital tract and pelvic infection following ectopic and molar pregnancy | |
| ectopic or molar pregnancy | O08.82 | Sepsis following ectopic and molar pregnancy | |
| immunization | T88.0 | Infection following immunization | not billable |
| infusion, therapeutic injection or transfusion NEC | T80.29 | Infection following other infusion, transfusion and therapeutic injection | not billable |
| obstetrical procedure | O86.04 | Sepsis following an obstetrical procedure |
Sepsis Gram-negative
| anaerobic | A41.4 | Sepsis due to anaerobes |
Sepsis localized - code to specific localized infection
| in operation wound | T81.49 | Infection following a procedure, other surgical site | not billable |
Sepsis newborn
| specified NEC | P36.8 | Other bacterial sepsis of newborn | |
| due to › anaerobes NEC | P36.5 | Sepsis of newborn due to anaerobes | |
| due to › Escherichia coli | P36.4 | Sepsis of newborn due to Escherichia coli | |
| due to › Staphylococcus | P36.30 | Sepsis of newborn due to unspecified staphylococci | |
| due to › Streptococcus | P36.10 | Sepsis of newborn due to unspecified streptococci | |
| due to › Staphylococcus › aureus | P36.2 | Sepsis of newborn due to Staphylococcus aureus | |
| due to › Staphylococcus › specified NEC | P36.39 | Sepsis of newborn due to other staphylococci | |
| due to › Streptococcus › group B | P36.0 | Sepsis of newborn due to streptococcus, group B | |
| due to › Streptococcus › specified NEC | P36.19 | Sepsis of newborn due to other streptococci |
Sepsis severe
| with septic shock | R65.21 | Severe sepsis with septic shock |
Sepsis Staphylococcus, staphylococcal
Sepsis Streptococcus, streptococcal
| agalactiae | A40.1 | Sepsis due to streptococcus, group B | |
| neonatal | P36.10 | Sepsis of newborn due to unspecified streptococci | |
| pneumoniae | A40.3 | Sepsis due to Streptococcus pneumoniae | |
| pyogenes | A40.0 | Sepsis due to streptococcus, group A | |
| specified NEC | A40.8 | Other streptococcal sepsis | |
| group › A | A40.0 | Sepsis due to streptococcus, group A | |
| group › B | A40.1 | Sepsis due to streptococcus, group B | |
| group › D | A41.81 | Sepsis due to Enterococcus | |
| neonatal › group B | P36.0 | Sepsis of newborn due to streptococcus, group B | |
| neonatal › specified NEC | P36.19 | Sepsis of newborn due to other streptococci |
Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources