A41.81 — Sepsis due to Enterococcus
Is A41.81 billable?
Yes — A41.81 is billable for FY2027. A41.81 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. A41.81 may be submitted for encounters from October 1, 2026 through September 30, 2027.
A41.81 at a glance
| Code | A41.81 |
|---|---|
| Description | Sepsis due to Enterococcus |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does A41.81 group to?
A41.81 sits in MDC 15 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 791Prematurity with Major Problemsmedical
As a secondary diagnosis, A41.81 is a major complication or comorbidity (MCC), which can move a stay into a higher-paying DRG.
How is A41.81 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to A41.81. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Sepsis › Enterococcus (generalized) (unspecified organism)
- Sepsis › Streptococcus, streptococcal › group › D (generalized) (unspecified organism)
Excludes1 — never code together — inherited from A41
The conditions below can never be reported together with A41.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Code first — inherited from A41
The underlying condition below must be sequenced before A41.81. A41.81 describes a manifestation and cannot be the principal or first-listed diagnosis.
- , if applicable, postprocedural sepsis (T81.44-)
- sepsis due to central venous catheter (T80.211-)
- sepsis during labor (O75.3)
- sepsis following abortion, ectopic or molar pregnancy (O03.37, O03.87, O04.87, O07.37, O08.82)
- sepsis following immunization (T88.0-)
- sepsis following infusion, transfusion or therapeutic injection (T80.22-, T80.29-)
Use additional code — inherited from Chapter 1
Report an additional code alongside A41.81 to fully describe the condition. A41.81 is sequenced first.
- code to identify resistance to antimicrobial drugs (Z16.-)
Excludes2 — not included here — inherited from Chapter 1
The conditions below are not part of A41.81, but a patient may have both at the same time. When documentation supports it, A41.81 and the excluded code may both be reported.
- carrier or suspected carrier of infectious disease (Z22.-)
- certain localized infections - see body system-related chapters
- infectious and parasitic diseases complicating pregnancy, childbirth and the puerperium (O98.-)
- infectious and parasitic diseases specific to the perinatal period (P35-P39)
- influenza and other acute respiratory infections (J00-J22)
Excludes2 — not included here — inherited from A41
The conditions below are not part of A41.81, but a patient may have both at the same time. When documentation supports it, A41.81 and the excluded code may both be reported.
- sepsis (due to) (in) actinomycotic (A42.7)
- sepsis (due to) (in) anthrax (A22.7)
- sepsis (due to) (in) candidal (B37.7)
- sepsis (due to) (in) Erysipelothrix (A26.7)
- sepsis (due to) (in) extraintestinal yersiniosis (A28.2)
- sepsis (due to) (in) gonococcal (A54.86)
- sepsis (due to) (in) herpesviral (B00.7)
- sepsis (due to) (in) listerial (A32.7)
- sepsis (due to) (in) melioidosis (A24.1)
- sepsis (due to) (in) meningococcal (A39.2-A39.4)
- sepsis (due to) (in) plague (A20.7)
- sepsis (due to) (in) tularemia (A21.7)
- toxic shock syndrome (A48.3)
How long has A41.81 existed?
A41.81 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.