ICD-10 Code for Hypercholesterolemia

Also indexed as (essential) (primary) (pure)

The ICD-10-CM code for hypercholesterolemia is E78.00 — Pure hypercholesterolemia, unspecified. This is the code the Alphabetic Index gives for hypercholesterolemia with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).

BillableUnspecified

E78.00 is billable but unspecified. If the documentation names a type, site or cause, one of the more specific codes below is likely expected.

Which hypercholesterolemia code should you use?

The Alphabetic Index lists 6 codes under Hypercholesterolemia. Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.

By type

with hyperglyceridemia, endogenous	E78.2	Mixed hyperlipidemia
dietary counseling and surveillance	Z71.3	Dietary counseling and surveillance
familial	E78.019	Familial hypercholesterolemia, unspecified
hereditary	E78.019	Familial hypercholesterolemia, unspecified

Hypercholesterolemia familial

homozygous [HoFH]	E78.010	Homozygous familial hypercholesterolemia [HoFH]
heterozygous [HeFH]	E78.011	Heterozygous familial hypercholesterolemia [HeFH]

Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources