Z88 — Allergy status to drugs, medicaments and biological substances

Not billable

Is Z88 billable?

No — Z88 is a non-billable header code. Z88 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 10 billable codes beneath Z88.

Billable codes under this header

Z88 at a glance

Code	Z88
Description	Allergy status to drugs, medicaments and biological substances
Billable	No — header code
Code set	ICD-10-CM FY2027
Valid for encounters	October 1, 2026 – September 30, 2027

Excludes2 — not included here

The conditions below are not part of Z88, but a patient may have both at the same time. When documentation supports it, Z88 and the excluded code may both be reported.

Allergy status, other than to drugs and biological substances (Z91.0-)

Code also — inherited from Z77-Z99

Two codes may be needed to describe the condition fully. Whether Z88 is sequenced first depends on the reason for the encounter.

any follow-up examination (Z08-Z09)

What codes fall under Z88? (10)

How long has Z88 existed?

Z88 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.