Z88.8 — Allergy status to other drugs, medicaments and biological substances
Is Z88.8 billable?
Yes — Z88.8 is billable for FY2027. Z88.8 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. Z88.8 may be submitted for encounters from October 1, 2026 through September 30, 2027.
Z88.8 at a glance
| Code | Z88.8 |
|---|---|
| Description | Allergy status to other drugs, medicaments and biological substances |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
What Medicare edits apply to Z88.8?
The Medicare Code Editor screens inpatient claims before they are grouped. These edits name Z88.8 directly.
CMS will reject this code as the principal diagnosis on an inpatient claim. It describes something other than the condition chiefly responsible for the admission.
Which MS-DRGs does Z88.8 group to?
Z88.8 sits in MDC 23 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 951Other Factors Influencing Health Statusmedical
How is Z88.8 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to Z88.8. They show the wording a clinician may have documented, which often differs from the Tabular description.
- History › personal › allergy › drugs, medicaments and biological substances › specified NEC
- History › personal › allergy › medicinal agents › specified NEC
Excludes2 — not included here — inherited from Z88
The conditions below are not part of Z88.8, but a patient may have both at the same time. When documentation supports it, Z88.8 and the excluded code may both be reported.
- Allergy status, other than to drugs and biological substances (Z91.0-)
Code also — inherited from Z77-Z99
Two codes may be needed to describe the condition fully. Whether Z88.8 is sequenced first depends on the reason for the encounter.
- any follow-up examination (Z08-Z09)
How long has Z88.8 existed?
Z88.8 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
- FY2021Allergy status to other drugs, medicaments and biological substances statusAllergy status to other drugs, medicaments and biological substances
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
What other codes are in the Z88 family? (9)
- Z88.0Allergy status to penicillin
- Z88.1Allergy status to other antibiotic agents
- Z88.2Allergy status to sulfonamides
- Z88.3Allergy status to other anti-infective agents
- Z88.4Allergy status to anesthetic agent
- Z88.5Allergy status to narcotic agent
- Z88.6Allergy status to analgesic agent
- Z88.7Allergy status to serum and vaccine
- Z88.9Allergy status to unspecified drugs, medicaments and biological substances