Z15 — Genetic susceptibility to disease

Not billable

Is Z15 billable?

No — Z15 is a non-billable header code. Z15 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 14 billable codes beneath Z15.

Billable codes under this header

Z15 at a glance

Code	Z15
Description	Genetic susceptibility to disease
Billable	No — header code
Code set	ICD-10-CM FY2027
Valid for encounters	October 1, 2026 – September 30, 2027

Excludes1 — never code together

The conditions below can never be reported together with Z15 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

chromosomal anomalies (Q90-Q99)

Use additional code

Report an additional code alongside Z15 to fully describe the condition. Z15 is sequenced first.

code, if applicable, for any associated family history of the disease (Z80-Z84)

Includes

Conditions classified to Z15.

confirmed abnormal gene

What codes fall under Z15? (5)

How long has Z15 existed?

Z15 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.