Z15.068 — Genetic susceptibility to other malignant neoplasm of digestive system
Is Z15.068 billable?
Yes — Z15.068 is billable for FY2027. Z15.068 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. Z15.068 may be submitted for encounters from October 1, 2026 through September 30, 2027.
Z15.068 at a glance
| Code | Z15.068 |
|---|---|
| Description | Genetic susceptibility to other malignant neoplasm of digestive system |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
What Medicare edits apply to Z15.068?
The Medicare Code Editor screens inpatient claims before they are grouped. These edits name Z15.068 directly.
CMS will reject this code as the principal diagnosis on an inpatient claim. It describes something other than the condition chiefly responsible for the admission.
Which MS-DRGs does Z15.068 group to?
Z15.068 sits in MDC 23 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 951Other Factors Influencing Health Statusmedical
How is Z15.068 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to Z15.068. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Genetic › susceptibility to disease NEC › malignant neoplasm › biliary tract
- Genetic › susceptibility to disease NEC › malignant neoplasm › digestive system NEC
- Genetic › susceptibility to disease NEC › malignant neoplasm › gastric
- Genetic › susceptibility to disease NEC › malignant neoplasm › pancreas
Inclusion terms
Alternative wording in documentation that is classified to Z15.068.
- Genetic susceptibility to biliary tract cancer
- Genetic susceptibility to gastric cancer
- Genetic susceptibility to pancreatic cancer
- Genetic susceptibility to small bowel cancer
Excludes1 — never code together — inherited from Z15
The conditions below can never be reported together with Z15.068 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- chromosomal anomalies (Q90-Q99)
Code first — inherited from Z15.0
The underlying condition below must be sequenced before Z15.068. Z15.068 describes a manifestation and cannot be the principal or first-listed diagnosis.
Use additional code — inherited from Z15
Report an additional code alongside Z15.068 to fully describe the condition. Z15.068 is sequenced first.
- code, if applicable, for any associated family history of the disease (Z80-Z84)
Use additional code — inherited from Z15.0
Report an additional code alongside Z15.068 to fully describe the condition. Z15.068 is sequenced first.
- code, if applicable, for any personal history of malignant neoplasm (Z85.-)
How long has Z15.068 existed?
Z15.068 first appears in FY2026.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.