R78 — Findings of drugs and other substances, not normally found in blood

Not billable

Is R78 billable?

No — R78 is a non-billable header code. R78 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 13 billable codes beneath R78.

Billable codes under this header

R78 at a glance

Code	R78
Description	Findings of drugs and other substances, not normally found in blood
Billable	No — header code
Code set	ICD-10-CM FY2027
Valid for encounters	October 1, 2026 – September 30, 2027

Use additional code

Report an additional code alongside R78 to fully describe the condition. R78 is sequenced first.

code to identify any retained foreign body, if applicable (Z18.-)

Excludes2 — not included here

The conditions below are not part of R78, but a patient may have both at the same time. When documentation supports it, R78 and the excluded code may both be reported.

mental or behavioral disorders due to psychoactive substance use (F10-F19)

Excludes2 — not included here — inherited from Chapter 18

The conditions below are not part of R78, but a patient may have both at the same time. When documentation supports it, R78 and the excluded code may both be reported.

abnormal findings on antenatal screening of mother (O28.-)
certain conditions originating in the perinatal period (P04-P96)
signs and symptoms classified in the body system chapters
signs and symptoms of breast (N63, N64.5)

Excludes2 — not included here — inherited from R70-R79

The conditions below are not part of R78, but a patient may have both at the same time. When documentation supports it, R78 and the excluded code may both be reported.

abnormal findings on antenatal screening of mother (O28.-)
abnormalities of lipids (E78.-)
abnormalities of platelets and thrombocytes (D69.-)
abnormalities of white blood cells classified elsewhere (D70-D72)
coagulation hemorrhagic disorders (D65-D68)
diagnostic abnormal findings classified elsewhere - see Alphabetical Index
hemorrhagic and hematological disorders of newborn (P50-P61)

What codes fall under R78? (10)

How long has R78 existed?

R78 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.