N16 — Renal tubulo-interstitial disorders in diseases classified elsewhere
Is N16 billable?
Yes — N16 is billable for FY2027. N16 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. N16 may be submitted for encounters from October 1, 2026 through September 30, 2027.
N16 at a glance
| Code | N16 |
|---|---|
| Description | Renal tubulo-interstitial disorders in diseases classified elsewhere |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
What Medicare edits apply to N16?
The Medicare Code Editor screens inpatient claims before they are grouped. These edits name N16 directly.
This code describes a manifestation of an underlying disease. The underlying condition must be sequenced before it, so it can never be the principal or first-listed diagnosis.
Which MS-DRGs does N16 group to?
N16 sits in MDC 11 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 698Other Kidney and Urinary Tract Diagnoses with MCCmedical
- 699Other Kidney and Urinary Tract Diagnoses with CCmedical
- 700Other Kidney and Urinary Tract Diagnoses without CC/MCCmedical
How is N16 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to N16. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Disorder › tubulo-interstitial › brucellosis (of)
- Disorder › tubulo-interstitial › glycogen storage disease (of)
- Disorder › tubulo-interstitial › leukemia NEC (of)
- Disorder › tubulo-interstitial › lymphoma NEC (of)
- Disorder › tubulo-interstitial › mixed cryoglobulinemia (of)
- Disorder › tubulo-interstitial › multiple myeloma (of)
- Disorder › tubulo-interstitial › sepsis (of)
- Disorder › tubulo-interstitial › transplant rejection (of)
- Disorder › tubulo-interstitial › Wilson's disease (of)
- Pyelonephritis › in › brucellosis
- Pyelonephritis › in › cryoglobulinemia
- Pyelonephritis › in › glycogen storage disease
Excludes1 — never code together
The conditions below can never be reported together with N16 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- diphtheritic pyelonephritis and tubulo-interstitial nephritis (A36.84)
- pyelonephritis and tubulo-interstitial nephritis in candidiasis (B37.49)
- pyelonephritis and tubulo-interstitial nephritis in cystinosis (E72.04)
- pyelonephritis and tubulo-interstitial nephritis in salmonella infection (A02.25)
- pyelonephritis and tubulo-interstitial nephritis in sarcoidosis (D86.84)
- pyelonephritis and tubulo-interstitial nephritis in Sjogren syndrome (M35.04)
- pyelonephritis and tubulo-interstitial nephritis in systemic lupus erythematosus (M32.15)
- pyelonephritis and tubulo-interstitial nephritis in toxoplasmosis (B58.83)
- renal tubular degeneration in diabetes (E08-E13 with .29)
- syphilitic pyelonephritis and tubulo-interstitial nephritis (A52.75)
Code first
The underlying condition below must be sequenced before N16. N16 describes a manifestation and cannot be the principal or first-listed diagnosis.
Inclusion terms
Alternative wording in documentation that is classified to N16.
- Pyelonephritis
- Tubulo-interstitial nephritis
Excludes1 — never code together — inherited from N10-N16
The conditions below can never be reported together with N16 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- pyeloureteritis cystica (N28.85)
Excludes2 — not included here — inherited from Chapter 14
The conditions below are not part of N16, but a patient may have both at the same time. When documentation supports it, N16 and the excluded code may both be reported.
- certain conditions originating in the perinatal period (P04-P96)
- certain infectious and parasitic diseases (A00-B99)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
How long has N16 existed?
N16 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
Which codes are confused with N16?
ICD-10-CM declares these codes mutually exclusive with N16 — exactly one of each pair can be correct for a given encounter.