D81.81 — Biotin-dependent carboxylase deficiency
Is D81.81 billable?
No — D81.81 is a non-billable header code. D81.81 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 3 billable codes beneath D81.81.
D81.81 at a glance
| Code | D81.81 |
|---|---|
| Description | Biotin-dependent carboxylase deficiency |
| Billable | No — header code |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Excludes1 — never code together
The conditions below can never be reported together with D81.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- biotin-dependent carboxylase deficiency due to dietary deficiency of biotin (E53.8)
Inclusion terms
Alternative wording in documentation that is classified to D81.81.
- Multiple carboxylase deficiency
Excludes1 — never code together — inherited from D80-D89
The conditions below can never be reported together with D81.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from D81
The conditions below can never be reported together with D81.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- autosomal recessive agammaglobulinemia (Swiss type) (D80.0)
Excludes2 — not included here — inherited from Chapter 3
The conditions below are not part of D81.81, but a patient may have both at the same time. When documentation supports it, D81.81 and the excluded code may both be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Excludes2 — not included here — inherited from D80-D89
The conditions below are not part of D81.81, but a patient may have both at the same time. When documentation supports it, D81.81 and the excluded code may both be reported.
- human immunodeficiency virus [HIV] disease (B20)
What codes fall under D81.81? (3)
How long has D81.81 existed?
D81.81 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.