D75.81 — Myelofibrosis
Is D75.81 billable?
Yes — D75.81 is billable for FY2027. D75.81 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. D75.81 may be submitted for encounters from October 1, 2026 through September 30, 2027.
D75.81 at a glance
| Code | D75.81 |
|---|---|
| Description | Myelofibrosis |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
What Medicare edits apply to D75.81?
The Medicare Code Editor screens inpatient claims before they are grouped. These edits name D75.81 directly.
This code describes a manifestation of an underlying disease. The underlying condition must be sequenced before it, so it can never be the principal or first-listed diagnosis.
Which MS-DRGs does D75.81 group to?
D75.81 sits in MDC 17 and helps define the logic of 3 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 820Lymphoma and Leukemia with Major O.R. Procedures with MCCsurgical
- 821Lymphoma and Leukemia with Major O.R. Procedures with CCsurgical
- 822Lymphoma and Leukemia with Major O.R. Procedures without CC/MCCsurgical
As a secondary diagnosis, D75.81 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is D75.81 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to D75.81. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Myelofibrosis
- Anemia › myelofibrosis (essential) (general) (hemoglobin deficiency) (infantile) (primary) (profound)
- Myelofibrosis › secondary
- Osteosclerosis › myelofibrosis
Excludes1 — never code together
The conditions below can never be reported together with D75.81 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Code first
The underlying condition below must be sequenced before D75.81. D75.81 describes a manifestation and cannot be the principal or first-listed diagnosis.
- the underlying disorder, such as:
- malignant neoplasm of breast (C50.-)
Use additional code
Report an additional code alongside D75.81 to fully describe the condition. D75.81 is sequenced first.
Inclusion terms
Alternative wording in documentation that is classified to D75.81.
- Myelofibrosis NOS
- Secondary myelofibrosis NOS
Excludes2 — not included here — inherited from Chapter 3
The conditions below are not part of D75.81, but a patient may have both at the same time. When documentation supports it, D75.81 and the excluded code may both be reported.
- autoimmune disease (systemic) NOS (M35.9)
- certain conditions originating in the perinatal period (P00-P96)
- complications of pregnancy, childbirth and the puerperium (O00-O9A)
- congenital malformations, deformations and chromosomal abnormalities (Q00-Q99)
- endocrine, nutritional and metabolic diseases (E00-E88)
- human immunodeficiency virus [HIV] disease (B20)
- injury, poisoning and certain other consequences of external causes (S00-T88)
- neoplasms (C00-D49)
- symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified (R00-R94)
Excludes2 — not included here — inherited from D75
The conditions below are not part of D75.81, but a patient may have both at the same time. When documentation supports it, D75.81 and the excluded code may both be reported.
How long has D75.81 existed?
D75.81 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.