Excludes1 pair

T88.7- vs T88.8-

T88.7 and T88.8 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on T88.7
specified adverse effects of drugs and medicaments (A00-R94 and T80-T88.6, T88.8)
T88.7

Unspecified adverse effect of drug or medicament

Not billable
Chapter 19
Injury, poisoning and certain other consequences of external causes
Section
T80-T88
Use when the record says
  • Drug hypersensitivity NOS
  • Drug reaction NOS
Indexed under
  • Complication › chemotherapy NEC (antineoplastic)
  • Complication › drug NEC
  • Damage › medication
  • Effect, adverse › drugs and medicaments
  • Hypersensitive, hypersensitiveness, hypersensitivity › drug
T88.8

Other specified complications of surgical and medical care, not elsewhere classified

Not billable
Chapter 19
Injury, poisoning and certain other consequences of external causes
Section
T80-T88
Indexed under
  • Paraffinoma
  • Misadventure › specified NEC
  • Complication › electroshock therapy › specified NEC
  • Complication › phototherapy › specified NEC
  • Effect, adverse › medical care › specified NEC

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027