ICDcodes.org
FY2027

T88.6 — Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered

Not billable

Is T88.6 billable?

No — T88.6 is a non-billable header code. T88.6 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 3 billable codes beneath T88.6.

T88.6 at a glance

CodeT88.6
DescriptionAnaphylactic reaction due to adverse effect of correct drug or medicament properly administered
BillableNo — header code
Code setICD-10-CM FY2027
Valid for encountersOctober 1, 2026 – September 30, 2027

How is T88.6 listed in the Alphabetic Index?

These are the routes through the Alphabetic Index that lead to T88.6. They show the wording a clinician may have documented, which often differs from the Tabular description.

  • Shock › drug › due to correct substance properly administered
  • Allergy, allergic › shock › due to › adverse effect of correct medicinal substance properly administered (reaction) (to)
  • Shock › anaphylactic › due to drug or medicinal substance › correct substance properly administered

Excludes1 — never code together

The conditions below can never be reported together with T88.6 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.

  • anaphylactic reaction due to serum (T80.5-)
  • anaphylactic shock or reaction due to adverse food reaction (T78.0-)

Use additional code

Report an additional code alongside T88.6 to fully describe the condition. T88.6 is sequenced first.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)

Inclusion terms

Alternative wording in documentation that is classified to T88.6.

  • Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
  • Anaphylactoid reaction NOS

Use additional code — inherited from Chapter 19

Report an additional code alongside T88.6 to fully describe the condition. T88.6 is sequenced first.

  • code to identify any retained foreign body, if applicable (Z18.-)

Use additional code — inherited from T80-T88

Report an additional code alongside T88.6 to fully describe the condition. T88.6 is sequenced first.

  • code for adverse effect, if applicable, to identify drug (T36-T50 with fifth or sixth character 5)
  • code(s) to identify the specified condition resulting from the complication
  • code to identify devices involved and details of circumstances (Y62-Y82)

Excludes2 — not included here — inherited from Chapter 19

The conditions below are not part of T88.6, but a patient may have both at the same time. When documentation supports it, T88.6 and the excluded code may both be reported.

  • birth trauma (P10-P15)
  • obstetric trauma (O70-O71)

Excludes2 — not included here — inherited from T80-T88

The conditions below are not part of T88.6, but a patient may have both at the same time. When documentation supports it, T88.6 and the excluded code may both be reported.

  • any encounters with medical care for postprocedural conditions in which no complications are present, such as:
  • artificial opening status (Z93.-)
  • closure of external stoma (Z43.-)
  • fitting and adjustment of external prosthetic device (Z44.-)
  • burns and corrosions from local applications and irradiation (T20-T32)
  • complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
  • mechanical complication of respirator [ventilator] (J95.850)
  • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
  • postprocedural fever (R50.82)
  • specified complications classified elsewhere, such as:
  • cerebrospinal fluid leak from spinal puncture (G97.0)
  • colostomy malfunction (K94.0-)
  • disorders of fluid and electrolyte imbalance (E86-E87)
  • functional disturbances following cardiac surgery (I97.0-I97.1)
  • intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
  • ostomy complications (J95.0-, K94.-, N99.5-)
  • postgastric surgery syndromes (K91.1)
  • postlaminectomy syndrome NEC (M96.1)
  • postmastectomy lymphedema syndrome (I97.2)
  • postsurgical blind-loop syndrome (K91.2)
  • ventilator associated pneumonia (J95.851)

Excludes2 — not included here — inherited from T88

The conditions below are not part of T88.6, but a patient may have both at the same time. When documentation supports it, T88.6 and the excluded code may both be reported.

  • complication following infusion, transfusion and therapeutic injection (T80.-)
  • complication following procedure NEC (T81.-)
  • complications of anesthesia in labor and delivery (O74.-)
  • complications of anesthesia in pregnancy (O29.-)
  • complications of anesthesia in puerperium (O89.-)
  • complications of devices, implants and grafts (T82-T85)
  • complications of obstetric surgery and procedure (O75.4)
  • dermatitis due to drugs and medicaments (L23.3, L24.4, L25.1, L27.0-L27.1)
  • poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4)
  • specified complications classified elsewhere

What codes fall under T88.6? (3)

How long has T88.6 existed?

T88.6 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.

Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.

Which codes are confused with T88.6?

ICD-10-CM declares these codes mutually exclusive with T88.6 — exactly one of each pair can be correct for a given encounter.

Which conditions are coded to T88.6?

What other codes are in the T88 family? (9)