Excludes1 pair

T78- vs T88.6-

T78 and T88.6 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on T88.6
anaphylactic shock or reaction due to adverse food reaction (T78.0-)
T78

Adverse effects, not elsewhere classified

Not billable
Chapter 19
Injury, poisoning and certain other consequences of external causes
Section
T66-T78
T88.6

Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered

Not billable
Chapter 19
Injury, poisoning and certain other consequences of external causes
Section
T80-T88
Use when the record says
  • Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
  • Anaphylactoid reaction NOS
Indexed under
  • Shock › drug › due to correct substance properly administered
  • Allergy, allergic › shock › due to › adverse effect of correct medicinal substance properly administered
  • Shock › anaphylactic › due to drug or medicinal substance › correct substance properly administered

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027