ICDcodes.org
FY2027

R57 vs T88.6

R57 and T88.6 can never be reported together. ICD-10-CM declares them mutually exclusive with an Excludes1 note, meaning the two conditions cannot occur in the same patient — so exactly one of them is correct for any given encounter.

The official note, declared on R57
anaphylactic shock due to adverse effect of correct drug or medicament properly administered (T88.6)
R57

Shock, not elsewhere classified

Not billable
Chapter 18
Symptoms, signs and abnormal clinical and laboratory findings, not elsewhere classified
Section
R50-R69
T88.6

Anaphylactic reaction due to adverse effect of correct drug or medicament properly administered

Not billable
Chapter 19
Injury, poisoning and certain other consequences of external causes
Section
T80-T88
Use when the record says
  • Anaphylactic shock due to adverse effect of correct drug or medicament properly administered
  • Anaphylactoid reaction NOS
Indexed under
  • Shock › drug › due to correct substance properly administered
  • Allergy, allergic › shock › due to › adverse effect of correct medicinal substance properly administered (reaction) (to)
  • Shock › anaphylactic › due to drug or medicinal substance › correct substance properly administered

These two codes sit in different chapters of the Tabular List, which is usually the clearest signal that they describe different underlying processes rather than different degrees of the same one.

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027