Excludes1 pair
D56.8 vs D57-
D56.8 and D57 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.
The official note, declared on D56.8
sickle-cell anemia (D57.-)
D56.8
Other thalassemias
Billable
- Chapter 3
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Section
- D55-D59
Use when the record says
- Dominant thalassemia
- Hemoglobin C thalassemia
- Mixed thalassemia
- Thalassemia with other hemoglobinopathy
Indexed under
- Variants, thalassemic
- Hemoglobinopathy › with thalassemia
- Thalassemia › with other hemoglobinopathy
- Thalassemia › dominant
- Thalassemia › mixed
D57
Sickle-cell disorders
Not billable
- Chapter 3
- Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism
- Section
- D55-D59
Indexed under
- Arthropathy › gouty › in › sickle-cell disorders
Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027