ICD-10 Code for Syphilis
Also indexed as (acquired)
The ICD-10-CM code for syphilis is A53.9 — Syphilis, unspecified. This is the code the Alphabetic Index gives for syphilis with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).
BillableUnspecified
A53.9 is billable but unspecified. If the documentation names a type, site or cause, one of the more specific codes below is likely expected.
Which syphilis code should you use?
The Alphabetic Index lists 79 codes under Syphilis, syphilitic. Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.
By type
| abdomen | A52.79 | Other symptomatic late syphilis | |
| acoustic nerve | A52.15 | Late syphilitic neuropathy | |
| adenopathy | A51.49 | Other secondary syphilitic conditions | |
| adrenal | A52.79 | Other symptomatic late syphilis | |
| alopecia | A51.32 | Syphilitic alopecia | |
| anemia | A52.79 | Other symptomatic late syphilis | |
| aneurysm | A52.01 | Syphilitic aneurysm of aorta | |
| anus | A52.74 | Syphilis of liver and other viscera | |
| aorta | A52.02 | Syphilitic aortitis | |
| aortic | A52.03 | Syphilitic endocarditis | |
| arachnoid | A52.13 | Late syphilitic meningitis | |
| ataxia | A52.11 | Tabes dorsalis | |
| atrophoderma maculatum | A51.39 | Other secondary syphilis of skin | |
| auricular fibrillation | A52.06 | Other syphilitic heart involvement | |
| bladder | A52.76 | Other genitourinary symptomatic late syphilis | |
| bone | A52.77 | Syphilis of bone and joint | |
| brain | A52.17 | General paresis | |
| breast | A52.79 | Other symptomatic late syphilis | |
| bronchus | A52.72 | Syphilis of lung and bronchus | |
| bubo | A51.0 | Primary genital syphilis | |
| bulbar palsy | A52.19 | Other symptomatic neurosyphilis | |
| bursa | A52.78 | Syphilis of other musculoskeletal tissue | |
| cardiac decompensation | A52.06 | Other syphilitic heart involvement | |
| cardiovascular | A52.00 | Cardiovascular syphilis, unspecified | |
| central nervous system | A52.3 | Neurosyphilis, unspecified | |
| cerebral | A52.17 | General paresis | |
| cerebrospinal | A52.12 | Other cerebrospinal syphilis | |
| cerebrovascular | A52.05 | Other cerebrovascular syphilis | |
| cervix | A52.76 | Other genitourinary symptomatic late syphilis | |
| chancre | A51.0 | Primary genital syphilis | |
| Charcot's joint | A52.16 | Charcot's arthropathy (tabetic) | |
| chorioretinitis | A51.43 | Secondary syphilitic oculopathy | |
| ciliary body | A51.43 | Secondary syphilitic oculopathy | |
| colon | A52.74 | Syphilis of liver and other viscera | |
| combined spinal sclerosis | A52.11 | Tabes dorsalis | |
| condyloma | A51.31 | Condyloma latum | |
| congenital | A50.9 | Congenital syphilis, unspecified | |
| conjugal | A53.9 | Syphilis, unspecified | |
| conjunctiva | A52.71 | Late syphilitic oculopathy | |
| contact | Z20.2 | Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission | |
| cord bladder | A52.19 | Other symptomatic neurosyphilis | |
| cornea, late | A52.71 | Late syphilitic oculopathy | |
| coronary | A52.06 | Other syphilitic heart involvement | |
| coryza, congenital | A50.05 | Early congenital syphilitic rhinitis | |
| cranial nerve | A52.15 | Late syphilitic neuropathy | |
| dacryocystitis | A52.71 | Late syphilitic oculopathy | |
| degeneration, spinal cord | A52.12 | Other cerebrospinal syphilis | |
| dementia paralytica | A52.17 | General paresis | |
| destruction of bone | A52.77 | Syphilis of bone and joint | |
| dilatation, aorta | A52.01 | Syphilitic aneurysm of aorta | |
| due to blood transfusion | A53.9 | Syphilis, unspecified | |
| dura mater | A52.13 | Late syphilitic meningitis | |
| ear | A52.79 | Other symptomatic late syphilis | |
| early | A51.9 | Early syphilis, unspecified | |
| eighth nerve | A52.15 | Late syphilitic neuropathy | |
| endemic | A65 | Nonvenereal syphilis | |
| endocarditis | A52.03 | Syphilitic endocarditis | |
| epididymis | A52.76 | Other genitourinary symptomatic late syphilis | |
| epiglottis | A52.73 | Symptomatic late syphilis of other respiratory organs | |
| epiphysitis | A50.02 | Early congenital syphilitic osteochondropathy | |
| episcleritis | A52.71 | Late syphilitic oculopathy | |
| esophagus | A52.79 | Other symptomatic late syphilis | |
| eustachian tube | A52.73 | Symptomatic late syphilis of other respiratory organs | |
| exposure to | Z20.2 | Contact with and (suspected) exposure to infections with a predominantly sexual mode of transmission | |
| eye | A52.71 | Late syphilitic oculopathy | |
| eyelid | A52.71 | Late syphilitic oculopathy | |
| fallopian tube | A52.76 | Other genitourinary symptomatic late syphilis | |
| fracture | A52.77 | Syphilis of bone and joint | |
| gallbladder | A52.74 | Syphilis of liver and other viscera | |
| gastric | A52.74 | Syphilis of liver and other viscera | |
| general | A53.9 | Syphilis, unspecified | |
| genital | A51.0 | Primary genital syphilis | |
| glaucoma | A52.71 | Late syphilitic oculopathy | |
| gumma NEC | A52.79 | Other symptomatic late syphilis | |
| heart | A52.06 | Other syphilitic heart involvement | |
| hemianesthesia | A52.19 | Other symptomatic neurosyphilis | |
| hemianopsia | A52.71 | Late syphilitic oculopathy | |
| hemiparesis | A52.17 | General paresis | |
| hemiplegia | A52.17 | General paresis | |
| hepatic artery | A52.09 | Other cardiovascular syphilis | |
| hepatis | A52.74 | Syphilis of liver and other viscera | |
| hepatomegaly, congenital | A50.08 | Early visceral congenital syphilis | |
| Hutchinson's teeth | A50.52 | Hutchinson's teeth | |
| hyalitis | A52.71 | Late syphilitic oculopathy | |
| internal ear | A52.79 | Other symptomatic late syphilis | |
| intestine | A52.74 | Syphilis of liver and other viscera | |
| iris, iritis | A51.43 | Secondary syphilitic oculopathy | |
| joint | A52.77 | Syphilis of bone and joint | |
| keratitis | A50.31 | Late congenital syphilitic interstitial keratitis | |
| kidney | A52.75 | Syphilis of kidney and ureter | |
| lacrimal passages | A52.71 | Late syphilitic oculopathy | |
| larynx | A52.73 | Symptomatic late syphilis of other respiratory organs | |
| late | A52.9 | Late syphilis, unspecified | |
| latent | A53.0 | Latent syphilis, unspecified as early or late | |
| lens | A52.71 | Late syphilitic oculopathy | |
| leukoderma | A51.39 | Other secondary syphilis of skin | |
| lienitis | A52.79 | Other symptomatic late syphilis | |
| lip | A51.39 | Other secondary syphilis of skin | |
| Lissauer's paralysis | A52.17 | General paresis | |
| liver | A52.74 | Syphilis of liver and other viscera | |
| locomotor ataxia | A52.11 | Tabes dorsalis | |
| lung | A52.72 | Syphilis of lung and bronchus | |
| lymph gland | A51.49 | Other secondary syphilitic conditions | |
| lymphadenitis | A51.49 | Other secondary syphilitic conditions | |
| macular atrophy of skin | A51.39 | Other secondary syphilis of skin | |
| mediastinum | A52.73 | Symptomatic late syphilis of other respiratory organs | |
| meninges | A52.13 | Late syphilitic meningitis | |
| meningitis | A52.13 | Late syphilitic meningitis | |
| meningoencephalitis | A52.14 | Late syphilitic encephalitis | |
| meningovascular | A52.13 | Late syphilitic meningitis | |
| mesarteritis | A52.09 | Other cardiovascular syphilis | |
| middle ear | A52.77 | Syphilis of bone and joint | |
| mitral stenosis | A52.03 | Syphilitic endocarditis | |
| monoplegia | A52.17 | General paresis | |
| mouth | A51.39 | Other secondary syphilis of skin | |
| mucocutaneous | A51.39 | Other secondary syphilis of skin | |
| mulberry molars | A50.52 | Hutchinson's teeth | |
| muscle | A52.78 | Syphilis of other musculoskeletal tissue | |
| myocardium | A52.06 | Other syphilitic heart involvement | |
| nasal sinus | A52.73 | Symptomatic late syphilis of other respiratory organs |
Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources