ICD-10 Code for Susceptibility to Disease, Genetic

The ICD-10-CM code for susceptibility to Disease, Genetic is Z15.89 — Genetic susceptibility to other disease. This is the code the Alphabetic Index gives for susceptibility to Disease, Genetic with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).

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Which susceptibility to Disease, Genetic code should you use?

The Alphabetic Index lists 9 codes under Susceptibility to disease, genetic. Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.

By type

hereditary nonpolyposis colorectal cancerQA1.71Lynch syndrome
malignant neoplasmZ15.09Genetic susceptibility to other malignant neoplasm
multiple endocrine neoplasiaZ15.81Genetic susceptibility to multiple endocrine neoplasia [MEN]

Susceptibility to Disease, Genetic malignant neoplasm

breastZ15.01Genetic susceptibility to malignant neoplasm of breast
endometriumZ15.04Genetic susceptibility to malignant neoplasm of endometrium
fallopian tubeZ15.05Genetic susceptibility to malignant neoplasm of fallopian tube(s)
ovaryZ15.02Genetic susceptibility to malignant neoplasm of ovary
prostateZ15.03Genetic susceptibility to malignant neoplasm of prostate
specified NECZ15.09Genetic susceptibility to other malignant neoplasm

Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources