ICD-10 Code for Leukoencephalopathy
The ICD-10-CM code for leukoencephalopathy is G93.49 — Other encephalopathy. This is the code the Alphabetic Index gives for leukoencephalopathy with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).
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Which leukoencephalopathy code should you use?
The Alphabetic Index lists 12 codes under Leukoencephalopathy. Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.
By type
| adult-onset, with axonal spheroids | G93.44 | Adult-onset leukodystrophy with axonal spheroids | |
| Binswanger's | I67.3 | Progressive vascular leukoencephalopathy | |
| heroin vapor | G92.8 | Other toxic encephalopathy | |
| megalencephalic, with subcortical cysts | G93.42 | Megalencephalic leukoencephalopathy with subcortical cysts | |
| metachromatic | E75.25 | Metachromatic leukodystrophy | |
| multifocal | A81.2 | Progressive multifocal leukoencephalopathy | |
| postimmunization and postvaccinal | G04.02 | Postimmunization acute disseminated encephalitis, myelitis and encephalomyelitis | |
| progressive multifocal | A81.2 | Progressive multifocal leukoencephalopathy | |
| reversible, posterior | G93.6 | Cerebral edema | |
| van Bogaert's | A81.1 | Subacute sclerosing panencephalitis | |
| vascular, progressive | I67.3 | Progressive vascular leukoencephalopathy |
Leukoencephalopathy with
Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources