ICD-10 Code for Leukodystrophy
The ICD-10-CM code for leukodystrophy is G31.80 — Leukodystrophy, unspecified. This is the code the Alphabetic Index gives for leukodystrophy with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).
G31.80 is billable but unspecified. If the documentation names a type, site or cause, one of the more specific codes below is likely expected.
Which leukodystrophy code should you use?
The Alphabetic Index lists 5 codes under Leukodystrophy. Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.
By type
| with vanishing white matter disease | G11.6 | Leukodystrophy with vanishing white matter disease | |
| LMNB1-related autosomal dominant | G90.B | LMNB1-related autosomal dominant leukodystrophy | |
| metachromatic | E75.25 | Metachromatic leukodystrophy | |
| pol III-related | G11.5 | Hypomyelination - hypogonadotropic hypogonadism - hypodontia |
Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources