Codes by condition ICD-10 Code for Immunodeficiency The ICD-10-CM code for immunodeficiency is D84.9 — Immunodeficiency, unspecified. This is the code the Alphabetic Index gives for immunodeficiency with no further qualifier, valid for FY2027 (October 1, 2026 – September 30, 2027).
Billable Unspecified
D84.9 is billable but unspecified. If the documentation names a type, site or cause, one of the more specific codes below is likely expected.
Which immunodeficiency code should you use? The Alphabetic Index lists 33 codes under Immunodeficiency . Which one applies depends on the qualifier documented in the record — the type, site, cause, or associated condition. Find the qualifier below, then verify the code in the Tabular List before using it.
By type autosomal recessive, Swiss type D80.0 Hereditary hypogammaglobulinemia combined D81.9 Combined immunodeficiency, unspecified common variable D83.9 Common variable immunodeficiency, unspecified following hereditary defective response to Epstein-Barr virus D82.3 Immunodeficiency following hereditary defective response to Epstein-Barr virus severe combined D81.9 Combined immunodeficiency, unspecified specified type NEC D84.89 Other immunodeficiencies X-linked, with increased IgM D80.5 Immunodeficiency with increased immunoglobulin M [IgM]
Immunodeficiency with adenosine-deaminase deficiency D81.30 Adenosine deaminase deficiency, unspecified antibody defects D80.9 Immunodeficiency with predominantly antibody defects, unspecified hyperimmunoglobulinemia D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia increased immunoglobulin M D80.5 Immunodeficiency with increased immunoglobulin M [IgM] major defect D82.9 Immunodeficiency associated with major defect, unspecified partial albinism D82.8 Immunodeficiency associated with other specified major defects short-limbed stature D82.2 Immunodeficiency with short-limbed stature thrombocytopenia and eczema D82.0 Wiskott-Aldrich syndrome antibody defects › specified type NEC D80.8 Other immunodeficiencies with predominantly antibody defects major defect › specified type NEC D82.8 Immunodeficiency associated with other specified major defects
Immunodeficiency antibody with hyperimmunoglobulinemia D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia near-normal immunoglobulins D80.6 Antibody deficiency with near-normal immunoglobulins or with hyperimmunoglobulinemia
Immunodeficiency combined biotin-dependent carboxylase D81.819 Biotin-dependent carboxylase deficiency, unspecified severe D81.9 Combined immunodeficiency, unspecified specified type NEC D81.89 Other combined immunodeficiencies biotin-dependent carboxylase › biotinidase D81.810 Biotinidase deficiency biotin-dependent carboxylase › holocarboxylase synthetase D81.818 Other biotin-dependent carboxylase deficiency biotin-dependent carboxylase › specified type NEC D81.818 Other biotin-dependent carboxylase deficiency severe › with › low or normal B-cell numbers D81.2 Severe combined immunodeficiency [SCID] with low or normal B-cell numbers severe › with › low T- and B-cell numbers D81.1 Severe combined immunodeficiency [SCID] with low T- and B-cell numbers severe › with › reticular dysgenesis D81.0 Severe combined immunodeficiency [SCID] with reticular dysgenesis
Immunodeficiency common variable specified type NEC D83.8 Other common variable immunodeficiencies with › abnormalities of B-cell numbers and function D83.0 Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function with › autoantibodies to B- or T-cells D83.2 Common variable immunodeficiency with autoantibodies to B- or T-cells with › immunoregulatory T-cell disorders D83.1 Common variable immunodeficiency with predominant immunoregulatory T-cell disorders
Immunodeficiency due to conditions classified elsewhere D84.81 Immunodeficiency due to conditions classified elsewhere drugs D84.821 Immunodeficiency due to drugs external causes D84.822 Immunodeficiency due to external causes medication D84.821 Immunodeficiency due to drugs
Immunodeficiency selective, immunoglobulin A D80.2 Selective deficiency of immunoglobulin A [IgA] G D80.3 Selective deficiency of immunoglobulin G [IgG] subclasses M D80.4 Selective deficiency of immunoglobulin M [IgM]
Immunodeficiency severe combined due to adenosine deaminase deficiency D81.31 Severe combined immunodeficiency due to adenosine deaminase deficiency
Index terms and codes are reproduced from the official ICD-10-CM FY2027 release. The Alphabetic Index is a finding aid — a code must always be verified in the Tabular List before it is reported. Data sources