T80.52XS — Anaphylactic reaction due to vaccination, sequela
Is T80.52XS billable?
Yes — T80.52XS is billable for FY2027. T80.52XS is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. T80.52XS may be submitted for encounters from October 1, 2026 through September 30, 2027.
T80.52XS at a glance
| Code | T80.52XS |
|---|---|
| Description | Anaphylactic reaction due to vaccination, sequela |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
| 7th character "S" | sequela |
What does the 7th character "S" mean in T80.52XS?
In T80.52XS, the 7th character S means sequela. The 7th character is required for T80.52XS to be a valid, complete code.
Same condition, different episode of care — switch the 7th character:
Which MS-DRGs does T80.52XS group to?
T80.52XS sits in MDC 21 and helps define the logic of 2 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 922Other Injury, Poisoning and Toxic Effect Diagnoses with MCCmedical
- 923Other Injury, Poisoning and Toxic Effect Diagnoses without MCCmedical
How is T80.52XS listed in the Alphabetic Index?
The Alphabetic Index lists these routes under T80.52, the nearest indexed parent of T80.52XS. Use them to find the family, then select the specific code.
- Complication › vaccination › anaphylaxis NEC (s) (from) (of)
- Complication › vaccination › shock (s) (from) (of)
- Shock › anaphylactic › immunization
- Allergy, allergic › shock › due to › immunization (reaction) (to)
- Allergy, allergic › shock › due to › vaccination (reaction) (to)
- Complication › vaccination › serum intoxication, sickness, rash, or other serum reaction NEC › anaphylactic shock (s) (from) (of)
- Shock › anaphylactic › serum › immunization
- Shock › anaphylactic › serum › vaccination
Excludes1 — never code together — inherited from T80.5
The conditions below can never be reported together with T80.52XS on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- ABO incompatibility reaction due to transfusion of blood or blood products (T80.3-)
- allergic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock NOS (T78.2)
- anaphylactic reaction or shock due to adverse effect of correct medicinal substance properly administered (T88.6)
- other serum reaction (T80.6-)
Use additional code — inherited from Chapter 19
Report an additional code alongside T80.52XS to fully describe the condition. T80.52XS is sequenced first.
- code to identify any retained foreign body, if applicable (Z18.-)
Use additional code — inherited from T80-T88
Report an additional code alongside T80.52XS to fully describe the condition. T80.52XS is sequenced first.
Excludes2 — not included here — inherited from Chapter 19
The conditions below are not part of T80.52XS, but a patient may have both at the same time. When documentation supports it, T80.52XS and the excluded code may both be reported.
Excludes2 — not included here — inherited from T80-T88
The conditions below are not part of T80.52XS, but a patient may have both at the same time. When documentation supports it, T80.52XS and the excluded code may both be reported.
- any encounters with medical care for postprocedural conditions in which no complications are present, such as:
- artificial opening status (Z93.-)
- closure of external stoma (Z43.-)
- fitting and adjustment of external prosthetic device (Z44.-)
- burns and corrosions from local applications and irradiation (T20-T32)
- complications of surgical procedures during pregnancy, childbirth and the puerperium (O00-O9A)
- mechanical complication of respirator [ventilator] (J95.850)
- poisoning and toxic effects of drugs and chemicals (T36-T65 with fifth or sixth character 1-4 or 6)
- postprocedural fever (R50.82)
- specified complications classified elsewhere, such as:
- cerebrospinal fluid leak from spinal puncture (G97.0)
- colostomy malfunction (K94.0-)
- disorders of fluid and electrolyte imbalance (E86-E87)
- functional disturbances following cardiac surgery (I97.0-I97.1)
- intraoperative and postprocedural complications of specified body systems (D78.-, E36.-, E89.-, G97.3-, G97.4, H59.3-, H59.-, H95.2-, H95.3, I97.4-, I97.5, J95.6-, J95.7, K91.6-, L76.-, M96.-, N99.-)
- ostomy complications (J95.0-, K94.-, N99.5-)
- postgastric surgery syndromes (K91.1)
- postlaminectomy syndrome NEC (M96.1)
- postmastectomy lymphedema syndrome (I97.2)
- postsurgical blind-loop syndrome (K91.2)
- ventilator associated pneumonia (J95.851)
Excludes2 — not included here — inherited from T80
The conditions below are not part of T80.52XS, but a patient may have both at the same time. When documentation supports it, T80.52XS and the excluded code may both be reported.
- bone marrow transplant rejection (T86.01)
- febrile nonhemolytic transfusion reaction (R50.84)
- fluid overload due to transfusion (E87.71)
- posttransfusion purpura (D69.51)
- transfusion associated circulatory overload (TACO) (E87.71)
- transfusion (red blood cell) associated hemochromatosis (E83.111)
- transfusion related acute lung injury (TRALI) (J95.84)
How long has T80.52XS existed?
T80.52XS has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.