T45.8X5S — Adverse effect of other primarily systemic and hematological agents, sequela
Is T45.8X5S billable?
Yes — T45.8X5S is billable for FY2027. T45.8X5S is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. T45.8X5S may be submitted for encounters from October 1, 2026 through September 30, 2027.
T45.8X5S at a glance
| Code | T45.8X5S |
|---|---|
| Description | Adverse effect of other primarily systemic and hematological agents, sequela |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
| 7th character "S" | sequela |
What does the 7th character "S" mean in T45.8X5S?
In T45.8X5S, the 7th character S means sequela. The 7th character is required for T45.8X5S to be a valid, complete code.
Same condition, different episode of care — switch the 7th character:
What Medicare edits apply to T45.8X5S?
The Medicare Code Editor screens inpatient claims before they are grouped. These edits name T45.8X5S directly.
CMS will reject this code as the principal diagnosis on an inpatient claim. It describes something other than the condition chiefly responsible for the admission.
Which MS-DRGs does T45.8X5S group to?
T45.8X5S sits in MDC 21 and helps define the logic of 2 MS-DRGs (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 922Other Injury, Poisoning and Toxic Effect Diagnoses with MCCmedical
- 923Other Injury, Poisoning and Toxic Effect Diagnoses without MCCmedical
Excludes1 — never code together — inherited from T36-T50
The conditions below can never be reported together with T45.8X5S on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- toxic reaction to local anesthesia in pregnancy (O29.3-)
Code first — inherited from T36-T50
The underlying condition below must be sequenced before T45.8X5S. T45.8X5S describes a manifestation and cannot be the principal or first-listed diagnosis.
Use additional code — inherited from Chapter 19
Report an additional code alongside T45.8X5S to fully describe the condition. T45.8X5S is sequenced first.
- code to identify any retained foreign body, if applicable (Z18.-)
Use additional code — inherited from T36-T50
Report an additional code alongside T45.8X5S to fully describe the condition. T45.8X5S is sequenced first.
Excludes2 — not included here — inherited from Chapter 19
The conditions below are not part of T45.8X5S, but a patient may have both at the same time. When documentation supports it, T45.8X5S and the excluded code may both be reported.
Excludes2 — not included here — inherited from T36-T50
The conditions below are not part of T45.8X5S, but a patient may have both at the same time. When documentation supports it, T45.8X5S and the excluded code may both be reported.
Excludes2 — not included here — inherited from T45.8
The conditions below are not part of T45.8X5S, but a patient may have both at the same time. When documentation supports it, T45.8X5S and the excluded code may both be reported.
How long has T45.8X5S existed?
T45.8X5S has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.