T45.8 — Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents
Is T45.8 billable?
No — T45.8 is a non-billable header code. T45.8 groups more specific codes and cannot be submitted on a claim. A valid ICD-10-CM code must be reported at the highest level of specificity available in its branch. Select one of the 18 billable codes beneath T45.8.
Billable codes under this header
- T45.8X1APoisoning by other primarily systemic and hematological agents, accidental (unintentional), initial encounter
- T45.8X1DPoisoning by other primarily systemic and hematological agents, accidental (unintentional), subsequent encounter
- T45.8X1SPoisoning by other primarily systemic and hematological agents, accidental (unintentional), sequela
- T45.8X2APoisoning by other primarily systemic and hematological agents, intentional self-harm, initial encounter
- T45.8X2DPoisoning by other primarily systemic and hematological agents, intentional self-harm, subsequent encounter
- T45.8X2SPoisoning by other primarily systemic and hematological agents, intentional self-harm, sequela
- T45.8X3APoisoning by other primarily systemic and hematological agents, assault, initial encounter
- T45.8X3DPoisoning by other primarily systemic and hematological agents, assault, subsequent encounter
- T45.8X3SPoisoning by other primarily systemic and hematological agents, assault, sequela
- T45.8X4APoisoning by other primarily systemic and hematological agents, undetermined, initial encounter
- T45.8X4DPoisoning by other primarily systemic and hematological agents, undetermined, subsequent encounter
- T45.8X4SPoisoning by other primarily systemic and hematological agents, undetermined, sequela
- T45.8X5AAdverse effect of other primarily systemic and hematological agents, initial encounter
- T45.8X5DAdverse effect of other primarily systemic and hematological agents, subsequent encounter
- T45.8X5SAdverse effect of other primarily systemic and hematological agents, sequela
- T45.8X6AUnderdosing of other primarily systemic and hematological agents, initial encounter
- T45.8X6DUnderdosing of other primarily systemic and hematological agents, subsequent encounter
- T45.8X6SUnderdosing of other primarily systemic and hematological agents, sequela
T45.8 at a glance
| Code | T45.8 |
|---|---|
| Description | Poisoning by, adverse effect of and underdosing of other primarily systemic and hematological agents |
| Billable | No — header code |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Excludes2 — not included here
The conditions below are not part of T45.8, but a patient may have both at the same time. When documentation supports it, T45.8 and the excluded code may both be reported.
Inclusion terms
Alternative wording in documentation that is classified to T45.8.
- Poisoning by, adverse effect of and underdosing of liver preparations and other antianemic agents
- Poisoning by, adverse effect of and underdosing of natural blood and blood products
- Poisoning by, adverse effect of and underdosing of plasma substitute
Excludes1 — never code together — inherited from T36-T50
The conditions below can never be reported together with T45.8 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- toxic reaction to local anesthesia in pregnancy (O29.3-)
Code first — inherited from T36-T50
The underlying condition below must be sequenced before T45.8. T45.8 describes a manifestation and cannot be the principal or first-listed diagnosis.
Use additional code — inherited from Chapter 19
Report an additional code alongside T45.8 to fully describe the condition. T45.8 is sequenced first.
- code to identify any retained foreign body, if applicable (Z18.-)
Use additional code — inherited from T36-T50
Report an additional code alongside T45.8 to fully describe the condition. T45.8 is sequenced first.
Excludes2 — not included here — inherited from Chapter 19
The conditions below are not part of T45.8, but a patient may have both at the same time. When documentation supports it, T45.8 and the excluded code may both be reported.
Excludes2 — not included here — inherited from T36-T50
The conditions below are not part of T45.8, but a patient may have both at the same time. When documentation supports it, T45.8 and the excluded code may both be reported.
What codes fall under T45.8? (1)
How long has T45.8 existed?
T45.8 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
What other codes are in the T45 family? (10)
- T45.0Poisoning by, adverse effect of and underdosing of antiallergic and antiemetic drugsnot billable
- T45.1Poisoning by, adverse effect of and underdosing of antineoplastic and immunosuppressive drugsnot billable
- T45.2Poisoning by, adverse effect of and underdosing of vitaminsnot billable
- T45.3Poisoning by, adverse effect of and underdosing of enzymesnot billable
- T45.4Poisoning by, adverse effect of and underdosing of iron and its compoundsnot billable
- T45.5Poisoning by, adverse effect of and underdosing of anticoagulants and antithrombotic drugsnot billable
- T45.6Poisoning by, adverse effect of and underdosing of fibrinolysis-affecting drugsnot billable
- T45.7Poisoning by, adverse effect of and underdosing of anticoagulant antagonists, vitamin K and other coagulantsnot billable
- T45.9Poisoning by, adverse effect of and underdosing of unspecified primarily systemic and hematological agentnot billable
- T45.APoisoning by, adverse effect of and underdosing of immune checkpoint inhibitors and immunostimulant drugsnot billable