E74.4 — Disorders of pyruvate metabolism and gluconeogenesis
Is E74.4 billable?
Yes — E74.4 is billable for FY2027. E74.4 is a valid, billable ICD-10-CM code at the highest level of specificity in its branch. E74.4 may be submitted for encounters from October 1, 2026 through September 30, 2027.
E74.4 at a glance
| Code | E74.4 |
|---|---|
| Description | Disorders of pyruvate metabolism and gluconeogenesis |
| Billable | Yes |
| Code set | ICD-10-CM FY2027 |
| Valid for encounters | October 1, 2026 – September 30, 2027 |
Which MS-DRGs does E74.4 group to?
E74.4 sits in MDC 10 and helps define the logic of 1 MS-DRG (version 44, FY2027). Which one a stay actually groups to also depends on procedures and secondary diagnoses.
- 642Inborn and Other Disorders of Metabolismmedical
As a secondary diagnosis, E74.4 is a complication or comorbidity (CC), which can move a stay into a higher-paying DRG.
How is E74.4 listed in the Alphabetic Index?
These are the routes through the Alphabetic Index that lead to E74.4. They show the wording a clinician may have documented, which often differs from the Tabular description.
- Deficiency, deficient › phosphoenolpyruvate carboxykinase
- Disorder › gluconeogenesis (of)
- Disorder › pyruvate metabolism (of)
- Deficiency, deficient › pyruvate › carboxylase
- Deficiency, deficient › pyruvate › dehydrogenase
- Disorder › metabolism NOS › pyruvate (of)
Excludes1 — never code together
The conditions below can never be reported together with E74.4 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Inclusion terms
Alternative wording in documentation that is classified to E74.4.
- Deficiency of phosphoenolpyruvate carboxykinase
- Deficiency of pyruvate carboxylase
- Deficiency of pyruvate dehydrogenase
Excludes1 — never code together — inherited from Chapter 4
The conditions below can never be reported together with E74.4 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
- transitory endocrine and metabolic disorders specific to newborn (P70-P74)
Excludes1 — never code together — inherited from E70-E88
The conditions below can never be reported together with E74.4 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes1 — never code together — inherited from E74
The conditions below can never be reported together with E74.4 on the same claim. An Excludes1 note means the two conditions cannot occur in the same patient, so reporting both is a coding error.
Excludes2 — not included here — inherited from E70-E88
The conditions below are not part of E74.4, but a patient may have both at the same time. When documentation supports it, E74.4 and the excluded code may both be reported.
- Ehlers-Danlos syndromes (Q79.6-)
How long has E74.4 existed?
E74.4 has been in ICD-10-CM since at least FY2016, the earliest fiscal year on record here.
Derived from the official order files for FY2016–FY2026. FY2017 and FY2020 publish no order file, so those years are not covered.
Which codes are confused with E74.4?
ICD-10-CM declares these codes mutually exclusive with E74.4 — exactly one of each pair can be correct for a given encounter.
What other codes are in the E74 family? (6)
- E74.0Glycogen storage diseasenot billable
- E74.1Disorders of fructose metabolismnot billable
- E74.2Disorders of galactose metabolismnot billable
- E74.3Other disorders of intestinal carbohydrate absorptionnot billable
- E74.8Other specified disorders of carbohydrate metabolismnot billable
- E74.9Disorder of carbohydrate metabolism, unspecified