Excludes1 pair

N00- vs N10

N00 and N10 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on N00
acute tubulo-interstitial nephritis (N10)
N00

Acute nephritic syndrome

Not billable
Chapter 14
Diseases of the genitourinary system
Section
N00-N08
Use when the record says
  • acute glomerular disease
  • acute glomerulonephritis
  • acute nephritis
N10

Acute pyelonephritis

Billable
Chapter 14
Diseases of the genitourinary system
Section
N10-N16
Use when the record says
  • Acute infectious interstitial nephritis
  • Acute pyelitis
  • Acute tubulo-interstitial nephritis
  • Hemoglobin nephrosis
  • Myoglobin nephrosis
Indexed under
  • Nephrosis, nephrotic › hemoglobin
  • Nephrosis, nephrotic › myoglobin
  • Pyelitis › acute
  • Pyelonephritis › acute
  • Nephritis, nephritic › tubulo-interstitial › acute (infectious)

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027