Excludes1 pair

G35.A vs G37.9

G35.A and G37.9 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on G35.A
demyelinating disease of central nervous system, unspecified (G37.9)
G35.A

Relapsing-remitting multiple sclerosis

Billable
Chapter 6
Diseases of the nervous system
Section
G35-G37
Indexed under
  • Sclerosis, sclerotic › multiple › relapsing-remitting
G37.9

Demyelinating disease of central nervous system, unspecified

BillableUnspecified
Chapter 6
Diseases of the nervous system
Section
G35-G37
Use when the record says
  • Clinically isolated syndromes
Indexed under
  • Degeneration, degenerative › myelin, central nervous system
  • Demyelination, demyelinization › central nervous system
  • Disease, diseased › demyelinating, demyelinizating (nervous system)
  • Sclerosis, sclerotic › brain (generalized) (lobular)
  • Syndrome › clinically isolated

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027