Excludes1 pair

E71.3- vs E71.5-

E71.3 and E71.5 are not coded together. ICD-10-CM declares them mutually exclusive with an Excludes1 note — the two conditions are not expected to occur together, so exactly one of them is normally correct for a given encounter. The Official Guidelines carve out one exception: if the two conditions are clearly unrelated to each other, both may be reported.

The official note, declared on E71.3
peroxisomal disorders (E71.5)
E71.3

Disorders of fatty-acid metabolism

Not billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E70-E88
E71.5

Peroxisomal disorders

Not billable
Chapter 4
Endocrine, nutritional and metabolic diseases
Section
E70-E88
Indexed under
  • Aciduria › glutaric › type III

Excludes1 is not always absolute: where two conditions covered by the note are genuinely unrelated, CMS guidance permits reporting both. Document the reasoning rather than assuming it. More on Excludes1 vs Excludes2 · FY2027